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Maternal cortisol and anxiety levels obtained in the first half of pregnancy and in mid\u2010third trimester were found to be related to the gestational age of newborns, with higher levels of cortisol and\/or anxiety predicting greater chance of pre\u2010 or postmature birth. However, when measured over time, a greater increase in cortisol levels was more predictive of positive perinatal outcomes, such as no meconium in labor. 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