{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:51:46Z","timestamp":1786978306660,"version":"build-2736575974"},"reference-count":65,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Research in Nursing &amp; Health"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Men who have sex with men (MSM) in Thailand continue to experience a disproportionate HIV burden, with persistent challenges related to antiretroviral therapy (ART) adherence, quality of life, and self\u2010management. Stigma and the scarcity of culturally adapted interventions further hinder sustained engagement in care. This study evaluated the effectiveness of the HIV\/AIDS Self\u2010Management Education Program\u2013Thai (HASMEP\u2010T), a culturally adapted, nurse\u2010delivered, peer\u2010supported intervention, on immunologic and patient\u2010reported outcomes among Thai MSM living with HIV. A randomized controlled trial with a pretest\u2013posttest design was conducted at a tertiary HIV clinic, where 64 MSM living with HIV were randomized to either the intervention or control group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200932 each). The intervention included four biweekly, 3\u2009h group sessions over 7 weeks, in addition to routine services, while the control group received routine care only. Outcomes measured at baseline, immediately post\u2010intervention, and at the 12\u2010week follow\u2010up included CD4 count, ART adherence, quality of life (WHOQOL\u2010BREF), and HIV self\u2010management. Paired and independent\n                    <jats:italic>t<\/jats:italic>\n                    \u2010tests and repeated\u2010measures ANOVA were employed. At 12 weeks, the intervention group showed significantly greater improvements than the controls in CD4 count (+84.5\u2009cells\/mm\u00b3), ART adherence (+8.9%), quality of life (+14.7 points), and self\u2010management (+9.1 points) (all\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). No adverse events were observed. The findings indicate that HASMEP\u2010T is effective in enhancing immunologic, behavioral, and psychosocial outcomes among Thai MSM living with HIV and has the potential to be integrated into routine HIV care to strengthen ART adherence, reduce stigma, and improve quality of life in resource\u2010limited settings.\n                  <\/jats:p>","DOI":"10.1002\/nur.70046","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T13:44:12Z","timestamp":1765633452000},"page":"126-136","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of HASMEP\u2010Thai on CD4 Count and Health Outcomes in Thai MSM Living With HIV: A Randomized Controlled Trial"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4998-4760","authenticated-orcid":false,"given":"Natawan","family":"Khumsaen","sequence":"first","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1484-5950","authenticated-orcid":false,"given":"Anongluk","family":"Vongtree","sequence":"additional","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8876-3930","authenticated-orcid":false,"given":"Oradee","family":"Choksawat","sequence":"additional","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5709-8416","authenticated-orcid":false,"given":"Pissamai","family":"Wongsanga","sequence":"additional","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3698-5863","authenticated-orcid":false,"given":"Anchalee","family":"Thitasan","sequence":"additional","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9102-7879","authenticated-orcid":false,"given":"Kedsaraporn","family":"Kenbubpha","sequence":"additional","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1041-5658","authenticated-orcid":false,"given":"Samrej","family":"Tienthong","sequence":"additional","affiliation":[{"name":"Boromarajonani College of Nursing, Sanpasithiprasong, Faculty of Nursing Praboromarajanok Institute Muang Ubonratchathani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/S12879-020-05618-Y"},{"key":"e_1_2_10_3_1","volume-title":"Social Foundations of Thought and Action: A Social Cognitive Theory","author":"Bandura A.","year":"1986"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4278\/0890-1171-12.1.8"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0252623"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60821-6"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2196\/25107"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.37201\/req\/083.2021"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)30534-5"},{"key":"e_1_2_10_10_1","volume-title":"The Practice of Nursing Research: Appraisal, Synthesis and Generation of Evidence","author":"Burns N.","year":"2017"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17113808"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14193"},{"key":"e_1_2_10_13_1","volume-title":"Unending Work and Care: Managing Chronic Illness at Home","author":"Corbin J. 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