{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:07:07Z","timestamp":1773014827974,"version":"3.50.1"},"reference-count":76,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82474653"],"award-info":[{"award-number":["82474653"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Research in Nursing &amp; Health"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Type 2 diabetes mellitus (T2DM) affects the patient's quality of life. Currently, hypoglycemic drugs are mainly used for the standard care for T2DM, but they appear to cause many adverse reactions. As a traditional therapy, acupuncture has been gradually applied to the treatment of T2DM. However, the best acupuncture regimen is still uncertain. Therefore, we evaluated the clinical efficacy of various acupuncture therapies in the treatment of T2DM. Up to December 2nd, 2024, eight databases were searched. The data were analyzed using Stata 15.1 and R 4.2.1 software. The included studies were assessed for bias using the Cochrane risk of bias tool (RoB2.0). A total of 139 randomized controlled trials were included, involving 12,231 patients with T2DM. The results showed that compared with conventional treatment (CT), body acupuncture\u2009+\u2009CT had the best effect on improving fasting blood glucose (FBG) (MD\u2009=\u2009\u20130.84, 95% CI: \u20131.01, \u20130.67; SUCRA\u2009=\u200984.44%) and HbA1c (MD\u2009=\u2009\u20131.08, 95% CI: \u20131.42, \u20130.76; SUCRA\u2009=\u200987.44%); auricular acupuncture\u2009+\u2009CT had the best effect on improving 2\u2009h postprandial blood glucose (2hBG) (MD\u2009=\u2009\u20131.56, 95% CI: \u20132.05, \u20131.06: SUCRA\u2009=\u200982.10%), and laser acupuncture\u2009+\u2009CT had the best effect on improving homeostasis model assessment for insulin resistance (HOMA\u2010IR) (MD\u2009=\u2009\u20132.46, 95% CI: \u20135.85, 0.96; SUCRA\u2009=\u200983.95%), fasting insulin (FINS) (MD\u2009=\u2009\u20137.21, 95% CI: \u201319, 4.54; SUCRA\u2009=\u200982.00%) and overall response rate (RR\u2009=\u20091.45, 95% CI: 0.97, 2.31; SUCRA\u2009=\u200984.00%) Acupuncture can effectively improve diabetes related indicators. Body acupuncture, auricular acupuncture, and laser acupuncture appear to be the most advantageous options for managing T2DM. However, due to the low quality of the included studies, more evidence may be needed to verify the conclusions.<\/jats:p>","DOI":"10.1002\/nur.70054","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T11:09:32Z","timestamp":1770116972000},"page":"180-192","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acupuncture Therapy for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta\u2010Analysis"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9758-1670","authenticated-orcid":false,"given":"Ziyue","family":"Zhu","sequence":"first","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2356-8035","authenticated-orcid":false,"given":"Hai","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2868-2925","authenticated-orcid":false,"given":"Shuai","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1315-1997","authenticated-orcid":false,"given":"Renhong","family":"Wan","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9557-7069","authenticated-orcid":false,"given":"Luqiang","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3045-5131","authenticated-orcid":false,"given":"Xiaorui","family":"Zeng","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2261-9886","authenticated-orcid":false,"given":"Yupeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9838-3482","authenticated-orcid":false,"given":"Peng","family":"Lai","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5489-7034","authenticated-orcid":false,"given":"Qianhua","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Acupuncture\u2010Moxibustion Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9487-024X","authenticated-orcid":false,"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Office of Asset and Laboratory Management Chengdu University of TCM Chengdu China"},{"name":"Key Laboratory of Acupuncture for Senile Disease, Ministry of Education Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7554-0958","authenticated-orcid":false,"given":"Ying","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Acupuncture for Senile Disease, Ministry of Education Chengdu University of TCM Chengdu China"},{"name":"Graduate School Chengdu University of TCM Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"crossref","unstructured":"American Diabetes Association.2019. \u201c2. 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