{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:51:52Z","timestamp":1791118312791,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T00:00:00Z","timestamp":1369267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:p><jats:bold>Objective<\/jats:bold>: To evaluate the strength of association of body mass index (BMI) and waist circumference (WC) with incident heart failure (HF), exploring our associations by ethnicity and age.<\/jats:p><jats:p><jats:bold>Design and Methods<\/jats:bold>: 6,809 participants, aged 45\u201084 years old, without clinical cardiovascular disease (2000\u20132002), from the Multi\u2010Ethnic Study of Atherosclerosis were included. Cox\u2010Proportional hazards models were used to examine associations of BMI and WC with incident HF. The predictive abilities of BMI and WC were compared using receiver operating characteristic curves.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold>: Over a median follow\u2010up of 7.6 years, there were 176 cases. BMI and WC were associated with incident HF in men (1.33 [1.10\u20101.61] and 1.38 [1.18\u20101.62], respectively] and women (1.70 [1.33\u20102.17] and 1.64 [1.29\u20102.08], respectively). These associations became non\u2010significant after adjusting for obesity\u2010related conditions (hypertension, dysglycemia, hypercholesterolemia, left ventricular hypertrophy, kidney disease, and inflammation). The associations of BMI and WC did not vary significantly by ethnicity or age\u2010group, but were inverse in Hispanic men. The area under the curve for BMI and WC was 0.749 and 0.750, respectively, in men and 0.782 and 0.777, respectively, in women.<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold>: The association between obesity and incident HF is largely mediated by obesity\u2010related conditions. BMI and WC have similar predictive abilities for incident HF.<\/jats:p>","DOI":"10.1002\/oby.20298","type":"journal-article","created":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T07:14:19Z","timestamp":1357197259000},"page":"1915-1922","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["The relationship between measures of obesity and incident heart failure: The multi\u2010ethnic study of atherosclerosis"],"prefix":"10.1002","volume":"21","author":[{"given":"Imo A.","family":"Ebong","sequence":"first","affiliation":[{"name":"Department of Medicine University of Southern California Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"David C.","family":"Goff","sequence":"additional","affiliation":[{"name":"Colorado School of Public Health Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos 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