{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:14:12Z","timestamp":1780359252001,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T00:00:00Z","timestamp":1413417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The influence of the amount and rate of weight loss on subsequently regaining weight and dropout from treatment in severely obese patients targeting 5% weight loss was investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 120 consecutive hospital patients with severe obesity (BMI: 42\u2009\u00b1\u20099 kg\/m<jats:sup>2<\/jats:sup>) participated in an inpatient program targeting 5% weight loss that involved goal setting, charting weight four times daily, and diet and exercise. They were followed after discharge to assess subsequent regaining of weight and dropout.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean weight loss was 4.9\u2009\u00b1\u20092.4% after a mean of 19 days in the hospital, and 43% of the patients achieved the target weight loss (&gt;5%). Over the median 2\u2010year follow\u2010up period, greater than 5% in\u2010hospital weight loss was associated with a significantly lower risk of regaining weight after adjustment for various factors (&gt;5% to \u22647% loss: hazard ratio 0.30 [0.11\u20100.85] for regaining all of the lost weight and 0.32 [0.13\u20100.78] for regaining half of the lost weight). No significant relation between the amount or rate of weight loss and dropout from subsequent outpatient treatment was seen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Successfully achieving the target weight loss in a comprehensive program predicts subsequent maintenance of lower weight without increasing the risk of dropout. Successful in\u2010hospital weight loss might increase the motivation of obese patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.20874","type":"journal-article","created":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T16:51:57Z","timestamp":1413478317000},"page":"183-191","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Successfully achieving target weight loss influences subsequent maintenance of lower weight and dropout from treatment"],"prefix":"10.1002","volume":"23","author":[{"given":"Tomohide","family":"Yamada","sequence":"first","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Hara","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko Kishi","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiro","family":"Shojima","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Hosoe","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minaka","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshimasa","family":"Yamauchi","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kadowaki","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Metabolic Diseases, Graduate School of Medicine University of Tokyo  Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,16]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"WHO.Fact sheet on overweight and obesity [article online]. 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