{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:43:33Z","timestamp":1740149013292,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T00:00:00Z","timestamp":1534464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to examine the relationship between BMI and the incidence of rubella nonimmunity among pregnant women with regard to the World Health Organization categories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective cohort study of 117,063 eligible gravidas, managed between 1998 and 2015 in a university hospital of Hong Kong, China. BMI at antenatal booking was banded using the following World Health Organization definitions:\u2009&lt;\u200918.5 kg\/m<jats:sup>2<\/jats:sup>, 18.5 to 24.9 kg\/m<jats:sup>2<\/jats:sup>, 25.0 to 29.9 kg\/m<jats:sup>2<\/jats:sup>, and \u226530.0 kg\/m<jats:sup>2<\/jats:sup>. Maternal rubella nonimmunity status by BMI was assessed. Incidence rates were also assessed after adjusting for maternal advanced age, short stature\u2009&lt;\u2009151\u2009cm, mothers\u2019 birthplace, and postobstetric history covariates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Rubella nonimmunity incidence increased as the BMI increased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Gravidas with high BMI were more likely to be nonimmune if born in Hong Kong (odds ratio [OR], 1.234; 95% CI: 1.159\u20101.315; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) compared with those born outside of Hong Kong (OR, 1.066; 95% CI: 0.997\u20101.141; <jats:italic>P<\/jats:italic>\u2009=\u20090.063). After adjusting for covariates, women with BMI\u2009\u2265\u200925 kg\/m<jats:sup>2<\/jats:sup> had 1.127 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001; 95% CI: 1.074\u20101.182) greater odds of being nonimmune.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>High maternal BMI (\u2265 25.0 kg\/m<jats:sup>2<\/jats:sup>) is associated with reduced rubella immunity, an effect confined to gravidas with almost complete vaccine coverage in childhood.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.22244","type":"journal-article","created":{"date-parts":[[2018,8,18]],"date-time":"2018-08-18T06:48:10Z","timestamp":1534574890000},"page":"1392-1395","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Maternal BMI on Rubella Nonimmunity at Antenatal Screening"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5042-4731","authenticated-orcid":false,"given":"Shuk Yi Annie","family":"Hui","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong, Prince of Wales Hospital  Shatin Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daljit S.","family":"Sahota","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong, Prince of Wales Hospital  Shatin Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terence T.","family":"Lao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong, Prince of Wales Hospital  Shatin Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.010207"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082779"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.08.027"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2017.131"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2001.1139cn2155.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/BF03404484","article-title":"Serologic responses to measles, mumps, and rubella (MMR) vaccine in healthy infants: failure to respond to measles and mumps components may influence decisions on timing of the second dose of MMR","volume":"89","author":"Mitchell LA","year":"1998","journal-title":"Can J Public Health"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.10.130"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268810002748"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.09.075"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.02903.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12051"},{"key":"e_1_2_6_13_1","first-page":"17","article-title":"Rubella in Hong Kong","volume":"4","author":"Chan CM","year":"1995","journal-title":"Public Health and Epidemiology Bulletin"},{"key":"e_1_2_6_14_1","first-page":"585","article-title":"Mass measles immunization campaign: experience in the Hong Kong Special Administrative Region of China","volume":"80","author":"Chuang SK","year":"2002","journal-title":"Bull World Health Organ"},{"volume-title":"DH SEB CD\/10\/7 II: Hong Kong Childhood Immunisation Programme (2007)","year":"2006","author":"Tsang T","key":"e_1_2_6_15_1"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.12.052"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","unstructured":"NardoneA TischerA AndrewsN et al.Comparison of rubella seroepidemiology in 17 countries: progress towards international disease control targets. Bull World Health Organ2008;86:118\u2010125.","DOI":"10.2471\/BLT.07.042010"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183630"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.02.039"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(96)00310-6"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.04.016"}],"container-title":["Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Foby.22244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oby.22244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/oby.22244","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oby.22244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T07:00:58Z","timestamp":1694415658000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/oby.22244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,17]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1002\/oby.22244"],"URL":"https:\/\/doi.org\/10.1002\/oby.22244","archive":["Portico"],"relation":{},"ISSN":["1930-7381","1930-739X"],"issn-type":[{"type":"print","value":"1930-7381"},{"type":"electronic","value":"1930-739X"}],"subject":[],"published":{"date-parts":[[2018,8,17]]},"assertion":[{"value":"2017-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}