{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:12:59Z","timestamp":1790115179478,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002494"],"award-info":[{"award-number":["UL1TR002494"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007189","name":"UniHealth Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to examine whether 1\u2010month BMI improvement is predictive of superior 6\u2010 and 12\u2010month BMI changes in a national sample of youth in pediatric weight management treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were 4\u2010 to 18\u2010year\u2010olds from the Pediatric Obesity Weight Evaluation Registry, a prospective study collecting data from 31 pediatric weight management programs across the United States. Response at 1 month was defined as \u2265\u00a03% BMI reduction; success at 6 and 12 months was defined as \u2265\u00a05% BMI reduction from baseline. Analyses used linear and logistic regression with robust variance estimation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Primary analyses were completed with 687 participants (mean age 12.2 years). One\u2010month responders demonstrated significant improvements in BMI compared with nonresponders at 6 months (BMI, \u22122.05 vs. 0.05; %BMI, \u22125.81 vs. 0.23; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001 for all) and 12 months (BMI, \u22121.87 vs. 0.30; %BMI, \u22125.04 vs. 1.06; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001 for all). The odds of success for 1\u2010month responders were 9.64 (95% CI: 5.85\u201015.87; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) times that of nonresponders at 6 months and 5.24 (95% CI: 2.49\u201011.02; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) times that of nonresponders at 12 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In treatment\u2010seeking youth with obesity, early BMI reduction was significantly associated with greater long\u2010term BMI reduction. Nonresponders may benefit from early treatment redirection or intensification.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.22367","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T22:58:45Z","timestamp":1548370725000},"page":"272-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Long and Short of It: Early Response Predicts Longer\u2010Term Outcomes in Pediatric Weight Management"],"prefix":"10.1002","volume":"27","author":[{"given":"Amy C.","family":"Gross","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Minnesota Medical School Minneapolis Minnesota USA"},{"name":"Center for Pediatric Obesity Medicine University of Minnesota Medical School Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Kaizer","sequence":"additional","affiliation":[{"name":"Center for Pediatric Obesity Medicine University of Minnesota Medical School Minneapolis Minnesota USA"},{"name":"Department of Biostatistics and Informatics, Colorado School of Public Health University of Colorado\u2010Anschutz Medical Campus Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron S.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Minnesota Medical School Minneapolis Minnesota USA"},{"name":"Center for Pediatric Obesity Medicine University of Minnesota Medical School Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle D.","family":"Rudser","sequence":"additional","affiliation":[{"name":"Center for Pediatric Obesity Medicine University of Minnesota Medical School Minneapolis Minnesota USA"},{"name":"Division of Biostatistics University of Minnesota School of Public Health Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7506-9497","authenticated-orcid":false,"given":"Justin R.","family":"Ryder","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Minnesota Medical School Minneapolis Minnesota USA"},{"name":"Center for Pediatric Obesity Medicine University of Minnesota Medical School Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia R.","family":"Borzutzky","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Keck School of Medicine of USC, Diabetes and Obesity Program, Children\u2019s Hospital Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Santos","sequence":"additional","affiliation":[{"name":"The Pediatric Obesity Center, Connecticut Children\u2019s Medical Center Hartford Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared M.","family":"Tucker","sequence":"additional","affiliation":[{"name":"Helen DeVos Children\u2019s Hospital Grand Rapids Michigan USA"},{"name":"Department of Pediatrics and Human Development Michigan State University Grand Rapids Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer K.","family":"Yee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Endocrinology Harbor\u2010UCLA Medical Center, The Los Angeles Biomedical Research Institute at Harbor\u2010UCLA Torrance California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia K.","family":"Fox","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Minnesota Medical School Minneapolis Minnesota USA"},{"name":"Center for Pediatric Obesity Medicine University of Minnesota Medical School Minneapolis Minnesota 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