{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:51:06Z","timestamp":1786978266230,"version":"build-2736575974"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T00:00:00Z","timestamp":1555977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Beijing Training Project for the Leading Talents in S & T","award":["2011LJ07"],"award-info":[{"award-number":["2011LJ07"]}]},{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"crossref","award":["7174286"],"award-info":[{"award-number":["7174286"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Beijing Health System Leading Talent Grant","award":["2009-1-08"],"award-info":[{"award-number":["2009-1-08"]}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"crossref","award":["2016YFC0900602"],"award-info":[{"award-number":["2016YFC0900602"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81473062"],"award-info":[{"award-number":["81473062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to describe the prevalence rates of abnormal metabolic phenotypes among urban Chinese children and to explore the impact of body composition as measured by dual\u2010energy x\u2010ray absorptiometry (DXA) on metabolic disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 7,926 children aged 6 to 17\u00a0years from seven cities across China were involved. Metabolically unhealthy was defined as having \u2265\u00a02 risk factors (elevated blood pressure, high triglyceride levels, low levels of high\u2010density lipoprotein cholesterol, and impaired fasting glucose [IFG]). Abnormal metabolic phenotypes were defined as metabolically unhealthy with normal weight (MUNW) and metabolically healthy with overweight or obesity (MHO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall prevalence rates of MUNW and MHO were 10.6% and 15.3%, respectively. The prevalence of MUNW increased with age in boys, whereas the prevalence in girls was statistically higher in 11\u2010 to 15\u2010year\u2010olds than in other age groups. The prevalence of MHO decreased with age in both genders. Among children with normal weight, the levels of body composition indices were positively correlated with metabolically unhealthy phenotype. Fat\u2010free mass had a protective effect on IFG in children with normal weight. Among children with overweight or obesity, body composition was related to elevated blood pressure and dyslipidemia but not to IFG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence rates of abnormal metabolic phenotypes differed between genders and ages. Body composition could partly explain the different metabolic phenotypes at the same BMI status among children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.22426","type":"journal-article","created":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T03:28:09Z","timestamp":1555990089000},"page":"837-844","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Abnormal Metabolic Phenotypes Among Urban Chinese Children: Epidemiology and the Impact of DXA\u2010Measured Body Composition"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1715-540X","authenticated-orcid":false,"given":"Fangfang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Epidemiology Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junting","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7758-744X","authenticated-orcid":false,"given":"Yinkun","family":"Yan","sequence":"additional","affiliation":[{"name":"Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0630-8447","authenticated-orcid":false,"given":"Jie","family":"Mi","sequence":"additional","affiliation":[{"name":"Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the China Child and Adolescent Cardiovascular Health (CCACH) Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60767-4"},{"key":"e_1_2_8_3_1","first-page":"1","article-title":"Empirical changes in the prevalence of overweight and obesity among Chinese students from 1985 to 2010 and corresponding preventive strategies","volume":"26","author":"Ji CY","year":"2013","journal-title":"Biomed Environ Sci"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.068"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047380"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv089"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-015-0560-7"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15269-5"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/beem.2002.0228"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2015.10.019"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2014.06.009"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2010.114"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2014.124"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.047"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2010.216"},{"key":"e_1_2_8_16_1","first-page":"1","article-title":"Assessing body fatness in obese adolescents: alternative methods to dual\u2010energy x\u2010ray absorptiometry","volume":"50","author":"Colley D","year":"2015","journal-title":"Digest (Wash D C)"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014542"},{"key":"e_1_2_8_18_1","first-page":"390","article-title":"Report on childhood obesity in China (1)\u2013body mass index reference for screening overweight and obesity in Chinese school\u2010age children","volume":"18","author":"Ji CY","year":"2005","journal-title":"Biomed Environ Sci"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-3988(10)60027-X"},{"key":"e_1_2_8_20_1","first-page":"428","article-title":"Updating blood pressure references for Chinese children aged 3\u201017\u00a0years","volume":"25","author":"Fan H","year":"2017","journal-title":"Chinese Journal of Hypertension"},{"key":"e_1_2_8_21_1","doi-asserted-by":"crossref","DOI":"10.1353\/book.26471","volume-title":"The Evolution of Obesity","author":"Power ML","year":"2009"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/60.1.23"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2001"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04085.x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2014.02.033"},{"key":"e_1_2_8_26_1","first-page":"401","article-title":"Disease risks of childhood obesity in China","volume":"18","author":"Li YP","year":"2005","journal-title":"Biomed Environ Sci"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.2147\/AHMT.S15942"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000246097.73031.27"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.11.2444"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1642"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12939"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1010112"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12198"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-1697"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/17477160802404509"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2011.247"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.7.777"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1262-3636(07)70156-8"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2013.208"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0165"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.2015.36.5.233"},{"key":"e_1_2_8_42_1","first-page":"14\u2010","volume-title":"Human Growth: A Comprehensive Treatise","author":"Marshall WA","year":"1986"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kws236"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1159\/000471488"}],"container-title":["Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Foby.22426","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oby.22426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T17:10:57Z","timestamp":1694365857000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/oby.22426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,23]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1002\/oby.22426"],"URL":"https:\/\/doi.org\/10.1002\/oby.22426","archive":["Portico"],"relation":{},"ISSN":["1930-7381","1930-739X"],"issn-type":[{"value":"1930-7381","type":"print"},{"value":"1930-739X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,23]]},"assertion":[{"value":"2018-10-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}