{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T22:29:59Z","timestamp":1788474599100,"version":"build-2803163510"},"reference-count":61,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,11,5]],"date-time":"2019-11-05T00:00:00Z","timestamp":1572912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Brown adipose tissue (BAT) is a thermogenic tissue with potential as a therapeutic target in the treatment of obesity and related metabolic disorders. The most used technique for quantifying human BAT activity is the measurement of <jats:sup>18<\/jats:sup>F\u2010fluorodeoxyglucose uptake via a positron emission tomography\/computed tomography scan following exposure to cold. However, several studies have indicated the measurement of the supraclavicular skin temperature (SST) by infrared thermography (IRT) to be a less invasive alternative. This work reviews the state of the art of this latter method as a means of determining BAT activity in humans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data sources for this review were PubMed, Web of Science, and EBSCOhost (SPORTdiscus), and eligible studies were those conducted in humans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In most studies in which participants were first cooled, an increase in IRT\u2010measured SST was noted. However, only 5 of 24 such studies also involved a nuclear technique that confirmed increased activity in BAT, and only 2 took into account the thickness of the fat layer when measuring SST\u00a0by IRT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>More work is needed to understand the involvement of tissues other than BAT in determining IRT\u2010measured SST; at present, IRT cannot determine whether any increase in SST is due to increased BAT activity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.22635","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T06:54:58Z","timestamp":1573023298000},"page":"1932-1949","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Infrared Thermography for Estimating Supraclavicular Skin Temperature and BAT Activity in Humans: A Systematic 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