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BMI growth was analyzed in the following three developmental periods: birth to 6 months, 6 months to 5 years, and 5 to 23 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Individuals with CM risks had a specific constellation of early\u2010life growth (faster growth after infancy, lower BMI decline approaching age 5, absence of a definitive BMI nadir in early childhood, higher 5\u2010year BMI) and distinct young adult growth (larger BMI increases from childhood to young adulthood and lower levels of expected growth deceleration approaching young adulthood). Those with CM risks also attained BMI\u2009\u2265\u200925 at significantly younger ages than those absent risks (metabolic syndrome: 12.3 years vs. 20.1 years; hyperglycemia: 13.1 years vs. 18.9 years; hypertension: 13.2 years vs. 19.4 years; hypertriglyceridemia: 14.3 years vs. 19.5 years; inflammation: 15.9 years vs. 20.6 years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Larger and faster increases in BMI and a failure of BMI growth to decline or decelerate at specific developmental periods distinguished individuals who would and would not have adult CM risks.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.22754","type":"journal-article","created":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T14:14:56Z","timestamp":1582899296000},"page":"813-821","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["BMI Trajectories from Birth to 23 Years by Cardiometabolic Risks in Young Adulthood"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5169-2735","authenticated-orcid":false,"given":"Patricia","family":"East","sequence":"first","affiliation":[{"name":"Department of Pediatrics School of Medicine University of California, San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Delker","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of California, San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estela","family":"Blanco","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of California, San Diego La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betsy","family":"Lozoff","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Correa","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Food Technology University of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9155-0689","authenticated-orcid":false,"given":"Raquel","family":"Burrows","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Food Technology University of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1105-7323","authenticated-orcid":false,"given":"Sheila","family":"Gahagan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of California, San Diego La Jolla California 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