{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:59:12Z","timestamp":1792979952035,"version":"4.5.0"},"reference-count":56,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T00:00:00Z","timestamp":1606176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007772","name":"Agir pour les Maladies Chroniques","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007772","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate (1) the effectiveness, complications, and postoperative access to transplantation in end\u2010stage chronic kidney disease (ECKD) and (2) the effectiveness and complications of bariatric surgery in patients who had already undergone kidney transplant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review and meta\u2010analysis of mortality and complications rates were performed. Thirty studies were reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After bariatric surgery, patients with ECKD had similar postoperative weight loss to patients from the general population. Meta\u2010analysis showed post\u2013bariatric surgery rates of 2% (95% CI: 0%\u20103%) for mortality and 7% (95% CI: 2%\u201014%) for complications. Approximately one\u2010fifth of the patients had access to a transplant. This rate may be underestimated because of the short duration of follow\u2010up. The lack of control groups did not allow for a conclusion on the role of bariatric surgery in facilitating access to kidney transplantation. In patients who had received a kidney transplant, bariatric surgery seemed to improve renal function but increased graft\u2010rejection risk, possibly because of changes in the bioavailability of immunosuppressant drugs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Bariatric surgery yields significant weight loss in patients with ECKD that improves patients\u2019 chances of accessing a transplant but does not guarantee it; however, the risk for complications and death is higher than in other patients. After transplantation, bariatric surgery\u2010induced weight loss appeared to positively impact the function of the grafted kidney, but careful monitoring of immunosuppressant medications is required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.23001","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T08:30:25Z","timestamp":1606206625000},"page":"2290-2304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Effectiveness and Safety of Bariatric Surgery in Patients with End\u2010Stage Chronic Kidney Disease or Kidney Transplant"],"prefix":"10.1002","volume":"28","author":[{"given":"Jessica","family":"Guggino","sequence":"first","affiliation":[{"name":"Endocrinology, Diabetology, Nutrition Grenoble Alpes University Hospital Grenoble 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