{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:45:47Z","timestamp":1747151147161,"version":"3.40.5"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K23\u2010DK105234","U01\u2010DK072493","R01\u2010DK080020"],"award-info":[{"award-number":["K23\u2010DK105234","U01\u2010DK072493","R01\u2010DK080020"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to assess associations between loss of control (LOC) eating and health outcomes among adolescents undergoing metabolic and bariatric surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 234 adolescents were studied before and up to 6 years after surgery in a prospective, observational cohort design. Adolescents provided self\u2010reports of LOC eating, pain severity, sleep quality, polycystic ovary syndrome, gastroesophageal reflux disease, and medication usage and objective measures of fasting glucose, serum insulin, glycohemoglobin A<jats:sub>1c<\/jats:sub>, cholesterol, triglycerides, and blood pressure. \u03c7<jats:sup>2<\/jats:sup> tests, Wilcoxon rank sums, and generalized linear mixed models were used to assess concurrent and prospective associations between LOC eating and health indicators.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LOC eating presented in 32.5% of adolescents before surgery and was positively associated with sleep disturbances and psychiatric medication usage. After surgery, LOC eating presented in 7.9% to 14.6% of participants and was correlated with improved low\u2010 and high\u2010density lipoprotein cholesterol levels and greater back pain. LOC eating was inversely associated with low\u2010density lipoprotein cholesterol at the next consecutive time point.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LOC eating was unexpectedly associated with improved low\u2010 and high\u2010density lipoprotein cholesterol in adolescents undergoing metabolic and bariatric surgery. Deleterious effects of LOC eating on obesity\u2010related health conditions, aside from back pain, were not detected. Metabolic and other weight\u2010independent health benefits of surgery may persist postoperatively despite LOC eating and associated weight regain.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.23126","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T06:10:53Z","timestamp":1616566253000},"page":"740-747","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Loss of Control Eating and Health Indicators Over 6 Years in Adolescents Undergoing Metabolic and Bariatric Surgery"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1620-8300","authenticated-orcid":false,"given":"Andrea B.","family":"Goldschmidt","sequence":"first","affiliation":[{"name":"Department of Psychiatry &amp; Human Behavior Alpert Medical School of Brown University The Miriam Hospital\/Weight Control and Diabetes Research Center Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane C.","family":"Khoury","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Epidemiology Department of Pediatrics Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James E.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neuroscience University of North Dakota School of Medicine and Health Sciences Fargo North Dakota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd M.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Surgery Department of Pediatrics Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine Cincinnati Ohio 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