{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:54:23Z","timestamp":1790286863327,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,6]],"date-time":"2022-03-06T00:00:00Z","timestamp":1646524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000130"],"award-info":[{"award-number":["UL1TR000130"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P01 CA168530"],"award-info":[{"award-number":["P01 CA168530"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA015704"],"award-info":[{"award-number":["P30 CA015704"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA071789"],"award-info":[{"award-number":["P30 CA071789"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U01 CA164973"],"award-info":[{"award-number":["U01 CA164973"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01 DK111698"],"award-info":[{"award-number":["R01 DK111698"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Given the importance of body fat distribution in chronic disease development, feasible methods to assess body fat are essential. This study compared dual\u2010energy x\u2010ray absorptiometry (DXA) in measuring visceral and subcutaneous adipose tissue (VAT and SAT) with magnetic resonance imaging (MRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>VAT and SAT were assessed using similar DXA and MRI protocols among 1,795 elderly participants of the Adiposity Phenotype Study (APS) and 309 children\/adolescents in Shape Up! Kids (SKids). Spearman correlations, Bland\u2013Altman plots, and coefficients of determination (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>) assessed agreement between DXA and MRI measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>DXA overestimated SAT values in APS (315 vs. 229 cm<jats:sup>2<\/jats:sup>) and SKids (212 vs. 161 cm<jats:sup>2<\/jats:sup>), whereas DXA underestimated VAT measures (141 vs. 167 cm<jats:sup>2<\/jats:sup>) in adults only. The correlations between DXA and MRI values were stronger for SAT than VAT (APS: <jats:italic>r<\/jats:italic> = 0.92 vs. 0.88; SKids: 0.90 vs. 0.74). Bland\u2013Altman plots confirmed better agreement for SAT than VAT despite differences by sex, ethnicity, and weight status with respective <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> values for SAT and VAT of 0.88 and 0.84 (APS) and 0.81 and 0.69 (SKids).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings indicate that SAT by DXA reflects MRI measures in children and older adults, whereas agreement for VAT is weaker for individuals with low VAT levels.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.23381","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T07:57:46Z","timestamp":1646639866000},"page":"920-930","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Subcutaneous and visceral fat assessment by DXA and MRI in older adults and children"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8129-958X","authenticated-orcid":false,"given":"Gertraud","family":"Maskarinec","sequence":"first","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurii B.","family":"Shvetsov","sequence":"additional","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2392-9253","authenticated-orcid":false,"given":"Michael C.","family":"Wong","sequence":"additional","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7563-0651","authenticated-orcid":false,"given":"Andrea","family":"Garber","sequence":"additional","affiliation":[{"name":"School of Medicine University of California at San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine","family":"Monroe","sequence":"additional","affiliation":[{"name":"Preventive Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Ernst","sequence":"additional","affiliation":[{"name":"Diagnostic Radiology and Nuclear Medicine University of Maryland  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Buchthal","sequence":"additional","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Unhee","family":"Lim","sequence":"additional","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5013-980X","authenticated-orcid":false,"given":"Lo\u00efc","family":"Le Marchand","sequence":"additional","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1127-9425","authenticated-orcid":false,"given":"Steven B.","family":"Heymsfield","sequence":"additional","affiliation":[{"name":"Pennington Biomedical Research Center  Baton Rouge Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2280-2541","authenticated-orcid":false,"given":"John A.","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Population Sciences in the Pacific University of Hawaii Cancer Center  Honolulu Hawaii USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00033.2011"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21028"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3048"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.303035"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2013.04.001"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2016.50"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nutd.2016.28"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nutd.2016.38"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jim-2018-000722"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.297"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2193723"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-020-0621-8"},{"key":"e_1_2_7_14_1","first-page":"93","article-title":"Predicting visceral adipose tissue by MRI using DXA and anthropometry in adolescents and young adults","volume":"10","author":"Laddu DR","year":"2012","journal-title":"Int J Body Compos Res"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20205"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.11.021"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22637"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nutd.2011.2"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00038-009-5405-9"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199710000-00011"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.459"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21561"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2018.04.011"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41430-020-0563-1"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.367"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.10.040"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1996.271.6.E941"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2017.06.010"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.126650"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2014.25"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqz218"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/80.15.1198"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.393"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20424"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20325"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41387-019-0073-1"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165275"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2012.95"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1708824"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.21037\/qims.2020.04.06"}],"container-title":["Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oby.23381","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/oby.23381","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oby.23381","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T20:45:53Z","timestamp":1692823553000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/oby.23381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,6]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1002\/oby.23381"],"URL":"https:\/\/doi.org\/10.1002\/oby.23381","archive":["Portico"],"relation":{},"ISSN":["1930-7381","1930-739X"],"issn-type":[{"value":"1930-7381","type":"print"},{"value":"1930-739X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,6]]},"assertion":[{"value":"2021-10-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}