{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:57:41Z","timestamp":1789736261149,"version":"4.0.1"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,25]],"date-time":"2022-09-25T00:00:00Z","timestamp":1664064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      This study aimed\u00a0to demonstrate noninferiority using telehealth in treating obesity with phentermine in patients with BMI\u2009\u2265\u200927 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      with comorbidities or BMI\u2009\u2265\u200930 compared with the standard in\u2010person approach over a 90\u2010day period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 12\u2010week, randomized, prospective, single\u2010center, open label trial compared the use of virtual visits versus in\u2010person visits for the treatment of obesity using phentermine. The primary end point was percentage mean change in body weight from baseline to 12\u2009weeks. A noninferiority approach assuming a 3% noninferiority region was used to assess effect size differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The weight loss in the virtual visit arm was noninferior to the in\u2010person arm at all time points. At 12\u2009weeks, the mean change in weight was \u22126.5% among the virtual group and \u22127.7% among the in\u2010person group. In addition, 65% of virtual patients and 71% of in\u2010person patients demonstrated a weight reduction of at least 5%. There was no difference in medication tolerance, adherence, and compliance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results indicate that the virtual obesity pharmacotherapy visits in adults aged 18 to 65\u2009years prescribed phentermine are effective and noninferior in achieving meaningful weight loss after 12\u2009weeks. Future clinical trials are needed to better assess the effectiveness of televisits for obesity pharmacotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.23548","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:44:40Z","timestamp":1664153080000},"page":"2194-2203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The use of virtual visits for obesity pharmacotherapy in patients with overweight or obesity compared with in\u2010person encounters"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5723-1182","authenticated-orcid":false,"given":"Marcio L.","family":"Griebeler","sequence":"first","affiliation":[{"name":"Endocrinology and Metabolism Institute Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7137-9423","authenticated-orcid":false,"given":"W. Scott","family":"Butsch","sequence":"additional","affiliation":[{"name":"Bariatric and Metabolic Department Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Institute Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Lomeli","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Institute Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Kampert","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Institute Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinni","family":"Makin","sequence":"additional","affiliation":[{"name":"Endocrinology and 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