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The aim of this study was to investigate whether women with PCOS have more weight\u2010loss attempts than women without PCOS, regardless of BMI. Moreover, women's weight perceptions in relation to previous weight\u2010loss attempts were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population\u2010based birth cohort study included women with (<jats:italic>n<\/jats:italic>\u00a0=\u00a0278) and without PCOS (control individuals, <jats:italic>n<\/jats:italic>\u00a0=\u00a01560) who were examined at ages 31 and 46\u2009years with questionnaires and clinical examinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Women with PCOS had more weight\u2010loss attempts compared with control individuals at age 31 (47% vs. 34%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and 46\u2009years (63% vs. 47%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). At age 46\u2009years, PCOS was associated with multiple weight\u2010loss attempts in the adjusted model (odds ratio: 1.43 [95% CI: 1.00\u20102.03], <jats:italic>p<\/jats:italic>\u00a0=\u00a00.05). The perception of having overweight was more prevalent in those with PCOS, even among participants with normal weight, at age 31 (PCOS 47% vs. control 34%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.014) and 46\u2009years (PCOS 60% vs. control 39%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Women with PCOS were more likely to have experienced multiple weight\u2010loss attempts and a perception of having overweight compared with control individuals, regardless of obesity status.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.23681","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T07:29:12Z","timestamp":1677655752000},"page":"1108-1120","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Polycystic ovary syndrome is associated with weight\u2010loss attempts and perception of overweight independent of BMI: a population\u2010based cohort study"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9789-4156","authenticated-orcid":false,"given":"Emilia","family":"Pesonen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine University of Oulu and Oulu University Hospital  Oulu Finland"},{"name":"Department of Sports and Exercise Medicine Oulu Deaconess Institute Foundation  Oulu Finland"},{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjukka","family":"Nurkkala","sequence":"additional","affiliation":[{"name":"Department of Sports and Exercise Medicine Oulu Deaconess Institute Foundation  Oulu Finland"},{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu Finland"},{"name":"Research Unit of Population Health University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maisa","family":"Niemel\u00e4","sequence":"additional","affiliation":[{"name":"Department of Sports and Exercise Medicine Oulu Deaconess Institute Foundation  Oulu Finland"},{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu Finland"},{"name":"Research Unit of Medical Imaging, Physics and Technology University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Morin\u2010Papunen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine University of Oulu and Oulu University Hospital  Oulu Finland"},{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha S.","family":"Tapanainen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine University of Oulu and Oulu University Hospital  Oulu Finland"},{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu Finland"},{"name":"Department of Obstetrics and Gynecology University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"J\u00e4ms\u00e4","sequence":"additional","affiliation":[{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu Finland"},{"name":"Research Unit of Medical Imaging, Physics and Technology University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raija","family":"Korpelainen","sequence":"additional","affiliation":[{"name":"Department of Sports and Exercise Medicine Oulu Deaconess Institute Foundation  Oulu Finland"},{"name":"Medical Research Center Oulu University Hospital and University of Oulu  Oulu 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