{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:43:54Z","timestamp":1764377034289,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T00:00:00Z","timestamp":1693872000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007878","name":"Diabetes Research Center","doi-asserted-by":"publisher","award":["P30 DK 036836"],"award-info":[{"award-number":["P30 DK 036836"]}],"id":[{"id":"10.13039\/100007878","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["RO1DK121995"],"award-info":[{"award-number":["RO1DK121995"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Bariatric surgery, a highly effective treatment for obesity and associated comorbidities, may improve cognition and brain volume in parallel with cardiometabolic function. However, some post\u2010bariatric individuals develop post\u2010bariatric hypoglycemia (PBH), which can be frequent and severe. The impact of recurrent hypoglycemia on cognition in PBH is unknown. The objective of this study was to determine whether individuals with PBH display reduced cognitive function compared with postsurgical counterparts without hypoglycemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fourteen adults with a history of Roux\u2010en\u2010Y gastric bypass with hypoglycemia (PBH+, <jats:italic>n<\/jats:italic>\u2009=\u20097) or without PBH (PBH\u2212, <jats:italic>n<\/jats:italic>\u2009=\u20097) completed assessments of memory, executive function, attention, and psychomotor speed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PBH+ individuals displayed significantly decreased performance in category fluency (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), category switching (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), and category switching accuracy (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), compared with PBH\u2212 individuals. Performance in the first (<jats:italic>p<\/jats:italic>\u2009=\u20090.03) and third intervals (<jats:italic>p<\/jats:italic>\u2009=\u20090.045) of verbal fluency was significantly lower in PBH+ individuals versus PBH\u2212 individuals. All other assessments did not differ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PBH+ individuals may be at greater risk for cognitive impairment compared with PBH\u2212 individuals, as suggested by impaired semantic processing and cognitive flexibility, as well as greater difficulty initiating and sustaining word retrieval.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.23862","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T07:55:50Z","timestamp":1693900550000},"page":"466-471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cognition in patients with <scp>post\u2010bariatric<\/scp> hypoglycemia"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9126-8314","authenticated-orcid":false,"given":"Alexa","family":"Puleio","sequence":"first","affiliation":[{"name":"Research Division Joslin Diabetes Center  Boston 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