{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:22:43Z","timestamp":1776162163557,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Information about excess adiposity markers different from BMI and iron status is limited and more so about the shape of these associations. This study evaluated the relationship between three adiposity markers and iron\u2010deficient status in reproductive\u2010age women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cross\u2010sectional analysis in 6357 non\u2010pregnant women from the Colombian nutritional health survey (ENSIN) 2010. Exposures were the following: waist circumference (WC), waist\u2010to\u2010height ratio (W\u2010HtR), BMI, and WC\u2009&gt;\u200980\u2009cm, W\u2010HtR\u2009&gt;\u20090.5, and BMI\u2009\u2265\u200925 and \u226530. Outcomes were the following: iron deficiency (ID) as serum ferritin &lt;15\u2009\u03bcg\/L, ID as ferritin &lt;30\u2009\u03bcg\/L, anemia, and continuous values of ferritin and hemoglobin. Logistic and linear regressions adjusted for sociodemographic\/inflammation covariates were conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All the adiposity markers, continuous or categorical, were inversely and significantly associated with both ID thresholds in fully adjusted models (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). W\u2010HtR reported stronger effect estimates for ID (odds ratios\u2009&lt;\u20090.5) and for prediction of log\u2010ferritin levels (fully adjusted \u03b2\u2010coefficient [95% CI] 0.61 [0.39\u20130.82],<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) and was also inversely associated with anemia (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). In cubic splines analyses, W\u2010HtR, WC, and BMI were linearly associated with ID from values closer to international thresholds of general or central obesity, and the patterns of WC and BMI tended toward flatness. A significant decline in the likelihood of anemia was steeper by increasing W\u2010HtR than by increasing BMI. After exclusion of women with C reactive protein\u2009&gt;\u2009\u20095\u2009mg\/L or adjustment for C reactive protein, adiposity markers remained significantly related to ferritin levels and W\u2010HtR with anemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Women with higher adiposity were less likely to have an iron\u2010deficient status. W\u2010HtR was the strongest and most consistently associated marker. Inflammation would not be involved in the associations found.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.23871","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T03:22:35Z","timestamp":1697080955000},"page":"3025-3042","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Excess adiposity and iron\u2010deficient status in Colombian women of reproductive age"],"prefix":"10.1002","volume":"31","author":[{"given":"Milton Fabi\u00e1n","family":"Suarez\u2010Orteg\u00f3n","sequence":"first","affiliation":[{"name":"Departamento de Alimentaci\u00f3n y Nutrici\u00f3n, Facultad de Ciencias de la Salud Pontificia Universidad Javeriana Seccional Cali Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny Elizabeth","family":"Ordo\u00f1ez\u2010Betancourth","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud Universidad Icesi Cali 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