{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:58:58Z","timestamp":1777395538538,"version":"3.51.4"},"reference-count":46,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR001873"],"award-info":[{"award-number":["UL1TR001873"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["P30DK26687"],"award-info":[{"award-number":["P30DK26687"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study was to assess maternal gestational outcomes and offspring growth trajectories following prepregnancy metabolic and bariatric surgery (MBS) compared with non\u2010MBS controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single\u2010center deliveries between January 2020 and March 2023 with prepregnancy Roux\u2010en\u2010Y gastric bypass (herein referred to as \u201cbypass\u201d), sleeve gastrectomy (herein referred to as \u201csleeve\u201d), and non\u2010MBS controls were included. Offspring growth trajectories were compared with the World Health Organization child growth standards. Linear mixed models assessed MBS\u2010bypass and MBS\u2010sleeve offspring weight, length, and BMI trajectories with a prepregnancy BMI 27 to 37\u2009kg\/m<jats:sup>2<\/jats:sup> and propensity score\u2010matched controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 440 participants with prepregnancy MBS (MBS\u2010bypass, 185; MBS\u2010sleeve, 225; 76% Hispanic\/Latino) and 13,434 non\u2010MBS controls. Gestational weight gain and gestational diabetes mellitus were similar, whereas hypertensive disorders of pregnancy were more common after MBS. The post\u2010MBS offspring had lower birth weight but higher weight gain at 24\u2009months (sleeve, +1.4\u2009kg [95% CI: 1.0\u20131.9]; bypass, +0.5\u20130.7\u2009kg [95% CI: 0.0\u20131.2]) compared with non\u2010MBS groups. Male children had higher weight gain than females. The post\u2010MBS\u2010sleeve but not the post\u2010MBS\u2010bypass offspring had higher BMI <jats:italic>z<\/jats:italic> scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The higher early\u2010life weight gain and sex differences in the post\u2010MBS\u2010sleeve group compared with the post\u2010MBS\u2010bypass group provide a window toward elucidating pathways to mitigate intergenerational metabolic risk transfer.<\/jats:p><jats:p><jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/oby24166-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1002\/oby.24166","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T08:52:45Z","timestamp":1730796765000},"page":"2012-2023","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The association of higher offspring early\u2010childhood weight gain with prepregnancy metabolic and bariatric surgery"],"prefix":"10.1002","volume":"32","author":[{"given":"Maya\u2010Jean","family":"Hilaire","sequence":"first","affiliation":[{"name":"Columbia College, Columbia University in the City of New York  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annelise","family":"Babcock","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn","family":"White","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia F.","family":"Masson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8816-6862","authenticated-orcid":false,"given":"Rany M.","family":"Salem","sequence":"additional","affiliation":[{"name":"Herbert Wertheim School of Public Health and Human Longevity Science University of California at San Diego  La Jolla California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uma M.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1769-9754","authenticated-orcid":false,"given":"Dympna","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2073-5050","authenticated-orcid":false,"given":"Charles A.","family":"LeDuc","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3537-2782","authenticated-orcid":false,"given":"Vidhu V.","family":"Thaker","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"March of Dimes Perinatal Data Center.https:\/\/www.marchofdimes.org\/peristats\/"},{"key":"e_1_2_11_3_1","unstructured":"Centers for Disease Control and Prevention.About natality 2016\u20132023 expanded. 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