{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:35:15Z","timestamp":1790231715572,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["200160\/2025\u20107"],"award-info":[{"award-number":["200160\/2025\u20107"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This longitudinal study aims to identify the key factors influencing the weight loss trajectory during a 24\u2010week intervention and their relevance at different stages of the treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We studied 1252 participants (age 18\u201365 years) of a cognitive behavioral program to lose weight. Body weight was measured weekly, and a range of variables at baseline and throughout the treatment period were assessed. Linear regression analyses were conducted to understand the factors involved in the weight loss trajectory across three treatment periods (0\u20136, 7\u201312, 13\u201324\u2009weeks).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The rate of weight loss progressively decreased from the 1st to the 3rd period (770\u2013198\u2009g\/week). During the 1st period, the recent history of the individual, including baseline metabolic status, dietary habits, and motivation, was the highest\u2010ranked determinant. In the 2nd\u00a0period, the sole predictor was the long\u2010term personal history of obesity, that is, the duration of the individual's lifetime spent with overweight\/obesity. In the 3rd period, emotional eating behaviors and related barriers emerged as the two highest\u2010ranked determinants of reduced rate of weight loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Findings suggest targeted interventions that address the specific challenges of each period of weight loss interventions. As treatment progresses, strategies focused on emotional\u2010related behaviors may be crucial for sustaining weight loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      identifier NCT02829619\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.70113","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T04:26:01Z","timestamp":1768969561000},"page":"357-371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Key Determinants of Weight Loss Trajectory Across Different Periods of a Behavioral Weight Loss Intervention"],"prefix":"10.1002","volume":"34","author":[{"given":"Roc\u00edo","family":"De la Pe\u00f1a\u2010Armada","sequence":"first","affiliation":[{"name":"Department of Nutrition and Food Science Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovana","family":"Longo\u2010Silva","sequence":"additional","affiliation":[{"name":"Department of Physiology University of Murcia  Murcia Spain"},{"name":"Faculty of Nutrition Federal University of Alagoas  Macei\u00f3 Alagoas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Rodr\u00edguez\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Physiology University of Murcia  Murcia Spain"},{"name":"Nutrition Group of Research Biomedical Research Institute of Murcia Pascual Parrilla\u2013IMIB  Murcia 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