{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T10:01:57Z","timestamp":1781085717877,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100015519","name":"WW International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015519","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Antiobesity medications (AOMs) are indicated for long\u2010term use; however, evidence of their real\u2010world long\u2010term efficacy is limited. This study describes clinical outcomes from 18\u2010 and 24\u2010month use of AOMs in a telemedicine weight management clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective observational study analyzed data from adult participants who utilized AOMs at a telemedicine weight management clinic between January 2022 and December 2024. Weight change analyses were conducted for those maintaining AOM use for \u2265\u200918\u2009months (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911,675) and \u2265\u200924\u2009months (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094317). Weight outcomes were assessed across all AOMs and stratified based on classification of AOMs utilized.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Across all AOMs, average total body weight reduction of \u221218.53% (95% CI: \u221218.74%, \u221218.32%) was observed at 18\u2009months and \u221220.27% (95% CI: \u221220.63%, \u221219.92%) seen at 24\u2009months. For those taking long\u2010acting AOMs, outcomes trended toward greater weight loss in comparison with participants using oral AOMs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This real\u2010world analysis found 18\u2010 and 24\u2010month weight losses comparable to those demonstrated in clinical trials, supporting the long\u2010term efficacy of AOMs provided by a telemedicine weight management clinic. Continued weight loss was demonstrated between 18 and 24\u2009months, suggesting sustained engagement with AOMs and a telemedicine weight management clinic support continued weight loss in the long term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.70156","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:05:32Z","timestamp":1772993132000},"page":"134-143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Twenty\u2010Four Month Outcomes From a Real\u2010World Telehealth Obesity Treatment Clinic Using Obesity Medications"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5721-1874","authenticated-orcid":false,"given":"Kathleen R.","family":"Ruddiman","sequence":"first","affiliation":[{"name":"Department of Surgery, Bariatric and Weight Management Section Wake Forest University School of Medicine  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young\u2010Rock","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Family and Preventive Medicine Emory University School of Medicine  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamy","family":"Ard","sequence":"additional","affiliation":[{"name":"Department of Surgery, Bariatric and Weight Management Section Wake Forest University School of Medicine  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Jones","sequence":"additional","affiliation":[{"name":"WW International, Inc.  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Medcalf","sequence":"additional","affiliation":[{"name":"WW International, Inc.  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3960-0332","authenticated-orcid":false,"given":"Gary D.","family":"Foster","sequence":"additional","affiliation":[{"name":"Center for Weight and Eating Disorders, Perelman School of Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9949-5119","authenticated-orcid":false,"given":"Jamil","family":"Alkhaddo","sequence":"additional","affiliation":[{"name":"WW International, Inc.  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Cardel","sequence":"additional","affiliation":[{"name":"WW International, Inc.  New York New York USA"},{"name":"Department of Health Outcomes and Biomedical Informatics University of Florida College of Medicine  Gainesville Florida USA"},{"name":"Center for Integrative Cardiovascular and Metabolic Disease University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,1]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.15620\/cdc\/159281"},{"key":"e_1_2_8_3_1","volume-title":"Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults: The Evidence Report","author":"National Heart, Lung, and Blood Institute","year":"1998"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22581"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamahealthforum.2024.2026"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.57232"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2023.02.003"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13752"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7149a6"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.70036"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.70069"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2196\/40062"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13734"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.23382"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.24169"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(21)00213\u20100"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206038"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411892"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14465"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(10)60888\u20104"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc19\u20100749"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100032\u20101327734"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.371"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X17745471"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/tmj.2019.0017"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.obpill.2024.100131"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1089\/tmj.2018.0002"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21854"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.793290"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.24177"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606\u2010023\u201008501\u2010z"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41366\u2010021\u201001019\u20106"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102661"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13326"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.57349"},{"issue":"4","key":"e_1_2_8_36_1","first-page":"A121","article-title":"Validity of Self\u2010Reported Height, Weight, and Body Mass Index: Findings From the National Health and Nutrition Examination Survey, 2001\u20102006","volume":"6","author":"Merrill R. 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