{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:30:06Z","timestamp":1782934206319,"version":"3.54.5"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the safety and effectiveness of metabolic and bariatric procedures (MBPs), including surgical and endoscopic interventions, among individuals with versus without heart failure (HF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter retrospective cohort study (2021\u20132023) identified persons with HF who underwent MBPs at two medical centers. Thirty\u2010day safety events and changes in body weight and medication use were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 1678 MBPs, 41 (2.4%) were performed in adults with HF (mean age, 51\u2009\u00b1\u200915\u2009years; 66% female; mean BMI, 44\u2009\u00b1\u20097\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Despite older age and more obesity\u2010related complications, persons with HF did not appear to experience a higher risk of any safety event at 30\u2009days versus those without HF (24% vs. 16%; adjusted OR, 1.64; 95% CI, 0.76\u20133.58;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.21). Thirty\u2010day change in body weight was similar between those with (\u22125.9%; 95% CI, \u22126.9%, \u22124.9%) and without HF (\u22126.2%; 95% CI, \u22126.4%, \u22126.0%;\n                      <jats:italic>p<\/jats:italic>\n                      <jats:sub>comparison<\/jats:sub>\n                      \u2009=\u20090.57). By 1 year, individuals with HF experienced significant reductions in body weight (mean change, \u221218.7%; 95% CI, \u221222.1%, \u221215.3%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), cardiovascular (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) and glucose\u2010lowering medications (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and loop diuretics (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that MBPs are safe and effective in well\u2010selected adults with obesity and HF. However, larger and prospective studies are warranted to enhance understanding of MBP risk\/benefit in this population.<\/jats:p>\n                    <jats:p>\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/oby70173-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.70173","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:59:28Z","timestamp":1773921568000},"page":"1151-1162","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Safety and Effectiveness of Metabolic and Bariatric Procedures in Heart Failure: A Multicenter Retrospective Cohort Study"],"prefix":"10.1002","volume":"34","author":[{"given":"John W.","family":"Ostrominski","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5803-9368","authenticated-orcid":false,"given":"Madeleine","family":"Schwede","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"Lodi","sequence":"additional","affiliation":[{"name":"Laboratory for Surgical and 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