{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T23:46:21Z","timestamp":1782517581206,"version":"3.54.5"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Higher short\u2010term weight variability (WV) predicts greater subsequent weight gain in weight\u2010stable adults and toddlers and lower long\u2010term weight loss among adults with overweight or obesity who previously lost weight. We extend prior work by examining the impact of naturally occurring WV on subsequent weight loss (weight at month 3 minus later weights) in individuals without obesity enrolled in the Comprehensive Assessment of the Long\u2010term Effects of Reducing Intake of Energy (CALERIE)\u00a0study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Participants (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009143) followed a 25% caloric restriction diet over 2\u2009years. WV was calculated as the root\u2010mean\u2010squared\u2010error of individuals' weights over the first 12\u2009weeks. Multilevel models examined WV's prediction of subsequent weight loss at 6, 12, 18, and 24 months relative to month 3, adjusting for baseline BMI, 12\u2010week weight change, and demographic variables. Sensitivity analyses further included time\u2010varying adherence and eating behaviors (disinhibition, restraint, craving).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Higher WV was associated with less subsequent weight loss at 6 months (\n                      <jats:italic>B<\/jats:italic>\n                      \u2009=\u2009\u22120.38, 95% CI [\u22120.63, \u22120.13],\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.16,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). The interaction between time and WV was not significant; analyses suggested the association extends through year 1.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Short\u2010term WV predicted lower subsequent weight loss in adults without obesity. Once its biobehavioral mechanisms are understood, WV might provide insight into humans' innate capacity for long\u2010term weight stability and inform future mechanistic research and clinical interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\/\">ClinicalTrials.gov<\/jats:ext-link>\n                      registration:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00427193\">NCT00427193<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.70235","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:27:09Z","timestamp":1781843229000},"page":"1409-1419","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prospective Association Between Weight Variability and Subsequent Long\u2010Term Weight Loss in the\n                    <scp>CALERIE<\/scp>\n                    Study"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1695-4143","authenticated-orcid":false,"given":"Branislav","family":"Jovanovic","sequence":"first","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania 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B.","family":"Roberts","sequence":"additional","affiliation":[{"name":"The Geisel School of Medicine Dartmouth College  Hanover New Hampshire USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Lowe","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences Drexel University  Philadelphia Pennsylvania 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