{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T11:46:37Z","timestamp":1793360797304,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to estimate extreme obesity prevalence and association with disease burden and outcomes in patients undergoing metabolic and bariatric surgery (MBS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Cross\u2010sectional data from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP, 2015\u20132023) were analyzed (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091,795,127). Preoperative disease burden and 30\u2010day outcomes were compared across BMI categories (&lt;\u200940, 40.0\u201349.9, 50.0\u201359.9, 60.0\u201369.9, 70.0\u201379.9, and \u2265\u200980\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), emphasizing extreme obesity compared to lower BMI categories.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Extreme obesity represented 5.3% of the eligible sample, though even higher BMI values (i.e., \u2265\u200970\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) were consistently present in 1.1% of cases annually (13,677 cases\/9\u2009years). Relative to BMI &lt;\u200940\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , patients with the highest BMI values (\u2265\u200970\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) had significantly greater frequency of hypertension (56.7% vs. 46.9%), sleep apnea (59.6% vs. 34.6%), COPD (2.6% vs. 1.1%), and functional dependence (4.5% vs. 0.5%). Increasing BMI category was associated with increased serious complications (2.6% vs. 0.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and mortality (0.35% vs. 0.05%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Extreme obesity is common in MBS, and greater BMI is associated with progressively higher comorbidity burden and complications. Despite the higher frequency of complications, absolute events are low and do not contraindicate multidisciplinary obesity treatment. Strategies to reduce preoperative BMI among patients with the highest BMI values warrant evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.70289","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T03:22:07Z","timestamp":1787628127000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Extreme Obesity (\n                    <scp>BMI<\/scp>\n                    \u2265\u200960\u2009kg\/m\n                    <sup>2<\/sup>\n                    ) Characterization up to and Beyond 80\u2009kg\/m\n                    <sup>2<\/sup>\n                    in 1,262,454 Bariatric Surgery Patients"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5267-8951","authenticated-orcid":false,"given":"Vance L.","family":"Albaugh","sequence":"first","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"},{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"},{"name":"Franciscan Missionaries of Our Lady Health  Baton Rouge Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector Garcia","family":"Navas","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"},{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert C.","family":"Ross","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"},{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8429-248X","authenticated-orcid":false,"given":"Florina","family":"Corpodean","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"},{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kachmar","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"},{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise M.","family":"Danos","sequence":"additional","affiliation":[{"name":"Department of Behavioral &amp; Community Health Louisiana State University School of Public Health  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1127-9425","authenticated-orcid":false,"given":"Steven B.","family":"Heymsfield","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9280-6022","authenticated-orcid":false,"given":"Peter","family":"Katzmarzyk","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"Cook","sequence":"additional","affiliation":[{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"},{"name":"University Medical Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip R.","family":"Schauer","sequence":"additional","affiliation":[{"name":"Metamor Institute, Pennington Biomedical Research Center  Baton Rouge Louisiana USA"},{"name":"Department of Surgery Louisiana State University Health Sciences Center  New Orleans Louisiana USA"},{"name":"Franciscan Missionaries of Our Lady Health  Baton Rouge Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/oby.70099","article-title":"Association of Obesity Severity With Cardiometabolic and Renal Disease Burden in the United States","volume":"34","author":"Corpodean F.","year":"2025","journal-title":"Obesity"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1001\/jama.2026.1114","article-title":"Obesity and Cancer","volume":"335","author":"Shen S.","year":"2026","journal-title":"JAMA"},{"key":"e_1_2_9_4_1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S2213-8587(25)00069-5","article-title":"Disproportionate Increase in BMI of \u226560 kg\/m2 in the USA","volume":"13","author":"Kachmar M.","year":"2025","journal-title":"Lancet Diabetes and Endocrinology"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2025.21170","article-title":"Prevalence of Extremely Severe Obesity and Metabolic Dysfunction Among US Children and Adolescents","volume":"8","author":"M\u00fcnte E.","year":"2025","journal-title":"JAMA Network Open"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/pm\/pnz184","article-title":"Weight Gain Trajectory and Pain Interference in Young Adulthood: Evidence From a Longitudinal Birth Cohort Study","volume":"21","author":"Tumin D.","year":"2020","journal-title":"Pain Medicine"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2105\/AJPH.2008.137364","article-title":"Small\u2010Area Estimation and Prioritizing Communities for Obesity Control in Massachusetts","volume":"99","author":"Li W.","year":"2011","journal-title":"American Journal of Public Health"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.amepre.2004.12.007","article-title":"Obesity Prevalence Among Veterans at Veterans Affairs Medical Facilities","volume":"28","author":"Das S. 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