{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T08:59:00Z","timestamp":1790413140344,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["209933838"],"award-info":[{"award-number":["209933838"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>BMI alone does not capture obesity\u2010related health heterogeneity. The Edmonton Obesity Staging System (EOSS) grades obesity severity based on comorbidities and functional impairment, whereas the Lancet Commission Diagnostic Model for Obesity (DMO) distinguishes preclinical from clinical obesity based on organ dysfunction. We compared classification patterns and concordance across both obesity frameworks in a large population\u2010based cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A modified EOSS and DMO were applied to the UK Biobank (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009\u2248\u2009411,000). Stage distributions, cross\u2010classification, and the impact of combining BMI with fat distribution on obesity categorization were analyzed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>About one\u2010quarter of participants were classified with obesity under both frameworks. Most were assigned to advanced stages, with high concordance for established disease. Differences were most pronounced in early stages: DMO captured a broader spectrum of mild\/subclinical organ dysfunction, whereas EOSS emphasized more advanced manifestations of obesity\u2010related disease. Discrepancies reflected differences in operationalization of, for example, metabolic, cardiovascular, and mental health domains. Obesity thresholds influenced classification, with ~50% reclassified when BMI was combined with different fat distribution parameters, highlighting the sensitivity of early\u2010stage assignment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EOSS and DMO provide complementary approaches to obesity classification, with differing classification patterns highlighting distinct concepts of obesity\u2010related disease severity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oby.70295","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T01:00:47Z","timestamp":1788310847000},"page":"1989-1998","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Divergent Obesity Classification Between the Edmonton Obesity Staging System and the Lancet Commission Model"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6146-8748","authenticated-orcid":false,"given":"Tobias","family":"Hagemann","sequence":"first","affiliation":[{"name":"Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI\u2010MAG) of the Helmholtz Zentrum M\u00fcnchen at the University of Leipzig and University Hospital Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9360-6519","authenticated-orcid":false,"given":"Arya M.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0208-2065","authenticated-orcid":false,"given":"Matthias","family":"Bl\u00fcher","sequence":"additional","affiliation":[{"name":"Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI\u2010MAG) of the Helmholtz Zentrum M\u00fcnchen at the University of Leipzig and University Hospital Leipzig  Leipzig Germany"},{"name":"Divisions of Endocrinology and Nephrology, Leipzig University Medical Center University of Leipzig  Leipzig Germany"},{"name":"LeiCeM \u2010 Leipzig Center of Metabolism Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3258-3397","authenticated-orcid":false,"given":"Anne","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI\u2010MAG) of the Helmholtz Zentrum M\u00fcnchen at the University of Leipzig and University Hospital Leipzig  Leipzig 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