{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:28:36Z","timestamp":1790612916422,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of the study is to evaluate the outcomes of surgical management options for cholesteatoma using a national database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Database analysis of the Pediatric Health Information System database to identify children undergoing surgical intervention for cholesteatoma from October 2015 to December 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients were categorized by initial surgical modality: tympanoplasty (TM), tympanoplasty with canal wall\u2010up tympanomastoidectomy (TM\u2010CWU), and tympanoplasty with canal wall\u2010down tympanomastoidectomy (TM\u2010CWD). Group comparisons were done on number of surgical revisions and number of patients identified with recommendations for hearing aids.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 6304 patients were identified in the database who underwent surgery for cholesteatoma. Of these children, 3405 underwent TM (54.0%), 3116 underwent TM\u2010CWU (49.4%), and 825 underwent TM\u2010CWD (8.2%). The estimated difference in mean number of procedures was significantly higher in the TM\u2010CWU group compared to TM\u2010CWD (\u22120.34, 95% confidence interval [CI] \u22120.406,\u22120.279,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001) and the TM group (9.352, 95% CI 0.315, 0.390,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001). The rate of significant hearing loss necessitating hearing aids was significantly lower in the TM group, but there was no difference between the TM\u2010CWU and TM\u2010CWD groups (1.2%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.03, 1.9% vs 2.7%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.13). There was no difference in the number of speech delays\/therapy diagnoses between TM and TM\u2010CWU or TM\u2010CWU and TM\u2010CWD (3.5%vs 4.4%\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.07, 4.4% vs 5.2%.,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.38).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>TM and TM\u2010CWD had lower total surgical procedures than the TM\u2010CWU group, and the TM group had a lesser rate of recommendation for hearing aids. The difference between number of procedures is likely due to the complexity of the disease; for instance, TM was likely chosen for small, less severe disease cases, whereas TM\u2010CWD was chosen as more definitive treatment in aggressive cases. TM\u2010CWD is associated with a lower rate of recidivism and recurrence, which also likely contributed to the lower number of procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.1025","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T11:24:19Z","timestamp":1729682659000},"page":"299-306","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes in Pediatric Cholesteatoma"],"prefix":"10.1002","volume":"172","author":[{"given":"Katherine M.","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Pediatric Otolaryngology Head and Neck Institute, Cleveland Clinic Foundation Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Chun Carol","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Texas Children's Hospital Houston Texas USA"},{"name":"Department of Pediatric Otolaryngology School of Medicine, Baylor College of Medicine Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaqueline E.","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Division of Pediatric Otolaryngology\u2013Head and Neck Surgery, Benioff Children's Hospital University of California\u2013San Francisco San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Harvard Medical School, Massachusetts Eye and Ear Infirmary Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Chi","sequence":"additional","affiliation":[{"name":"Departments of Otolaryngology University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Anne","sequence":"additional","affiliation":[{"name":"Department of Pediatric Otolaryngology Head and Neck Institute, Cleveland Clinic Foundation Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2021.110887"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2019.06.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.110170"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2019.05.003"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002876"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-018-0915-5"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20765"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000484"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.110080"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43163-020-00043-z"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joto.2018.11.009"},{"key":"e_1_2_9_13_1","first-page":"153","article-title":"Results of endoscopic middle ear surgery for cholesteatoma treatment: a systematic review","volume":"34","author":"Presutti L","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-012-0548-z"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.10.006"},{"key":"e_1_2_9_16_1","unstructured":"R Core Team.R: A Language and Environment for Statistical Computing.R Foundation for Statistical Computing;2019. 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