{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:38:49Z","timestamp":1762079929918,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To calculate the minimal clinically important difference (MCID) for the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM\u2010PATHI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>A single tertiary care balance and falls center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010three subjects meeting Barany Society criteria for vestibular migraine (VM) or probable VM were included and divided into 3 treatment groups. Treatment was not standardized, instead, management was decided individually between each patient and their provider. All subjects completed VM\u2010PATHI before and after intervention. A Global Rating of Change (GRoC) questionnaire was also completed following intervention. Anchor\u2010based methods, using a GRoC questionnaire, were utilized to estimate the MCID that produced the highest sensitivity and specificity on a receiver operating characteristic (ROC) curve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010three subjects were classified as responders and 10 were classified as nonresponders. The mean VM\u2010PATHI pretreatment score minus the posttreatment score between the responders (mean\u2009=\u200914, SD 13) and nonresponders (mean\u2009=\u20094 SD\u2009=\u200912) was statistically significant (mean difference\u2009=\u200910, 95% confidence interval, CI [1, 20], <jats:italic>P<\/jats:italic>\u2009=\u2009.03). The VM\u2010PATHI score change cutoff that best differentiated between responders and nonresponders was a VM\u2010PATHI change of 6. Thus, the MCID was defined as a change of 6 points (sensitivity\u2009=\u200972%, specificity\u2009=\u200970%). The area under the ROC curve was 0.89, 95% CI [0.80, 0.98], which demonstrates an excellent ability for the VM\u2010PATHI score change to discriminate between responders and nonresponders. The average change in VM\u2010PATHI scores was 9 points (SD 11) for those with \u201ca little better\u201d rating on the GRoC, 14 points (SD 14) for those with a \u201cmoderately better\u201d rating, and 20 points (SD 13) for those with a \u201cvery much better\u201d rating.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with VM are likely to demonstrate clinical improvement if their VM\u2010PATHI score decreases by 6 or more.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.1035","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T06:29:13Z","timestamp":1730269753000},"page":"623-628","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Minimal Clinically Important Difference of Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM\u2010PATHI)"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5860-2109","authenticated-orcid":false,"given":"Adam","family":"Gardi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of California, San Francisco (UCSF) San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxwell","family":"Hum","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of California, San Francisco (UCSF) San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of California, San Francisco (UCSF) San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics School of Medicine University of California, San Francisco (UCSF) San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey D.","family":"Sharon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of California, San Francisco (UCSF) San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_2_1","DOI":"10.1097\/MAO.0000000000001900"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_1","DOI":"10.3233\/VES-2012-0453"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.1097\/MAO.0000000000002561"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.1097\/MAO.0000000000004014"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.1016\/0197-2456(89)90005-6"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.1177\/0194599819852604"},{"doi-asserted-by":"publisher","key":"e_1_2_8_8_1","DOI":"10.1016\/S0895-4356(03)00044-1"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_1","DOI":"10.1016\/j.spinee.2007.01.008"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.1016\/j.rdc.2018.01.011"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1016\/j.apmr.2019.12.008"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_1","DOI":"10.1002\/9781118548387"},{"unstructured":"FormeisterEJ. Mindfulness\u2010based stress reduction for the treatment of vestibular migraine: a prospective trial. Presented at: Barany Society Meeting; May 9 2022; Madrid Spain.","key":"e_1_2_8_13_1"},{"unstructured":"SharonJD. A placebo controlled randomized clinical trial of galcanezumab for vestibular migraine: the INVESTMENT study. 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