{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:07:39Z","timestamp":1771045659939,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Surgical treatment of non\u2010obstructive sleep apnea (OSA) pathology poses the risk of inappropriate surgical indications. Herein, we sought to determine the prevalence of non\u2010OSA respiratory disorders, specifically central sleep apnea (CSA), in new referrals to a Sleep Surgery Clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective observational review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care academic medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a sleep surgery clinic cohort, the presence of clinically significant CSA was defined as having &gt;25% of the total apnea\u2010hypopnea index (AHI) being central and\/or mixed events. Demographics, comorbid disorders, patient\u2010reported outcome measurements, and sleep study results were compared among patients using linear or logistic regression analysis, unadjusted and adjusted for age, sex, and body mass index (BMI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On average, the cohort (n\u2009=\u2009295) was male (74%), middle\u2010aged (mean [\u00b1SD] 54.2\u2009\u00b1\u200913.9 years), and overweight (BMI 30.3\u2009\u00b1\u20095.4), with severe sleep apnea (AHI 30.6\u2009\u00b1\u200922.6\u2009events\/h). Twenty\u2010nine patients (9.8%) were found to have clinically significant CSA yet only 10% of these cases carried a diagnosis of CSA upon presentation. The remainder were identified by reviewing the pre\u2010visit sleep study tables (35%), raw data (17%), and tables and raw data of a repeat post\u2010visit study (38%). Patients with CSA were older and had evidence of more cardiac comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of CSA in new referrals to a Sleep Surgery Clinic was nearly 1 in 10 despite only 1% (3 of 295) with a known diagnosis upon presentation. Sleep surgeons must remain vigilant for patients with occult CSA, especially in older patients with a history of significant cardiovascular disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.1083","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T13:54:10Z","timestamp":1734011650000},"page":"686-692","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Prevalence of Central Sleep Apnea in New Referrals to a Sleep Surgery Clinic"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7391-5020","authenticated-orcid":false,"given":"Julianna G.","family":"Rodin","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology University of Pennsylvania Philadelphia Pennsylvania USA"},{"name":"Division of Sleep Medicine, Department of Medicine University of Pennsylvania Philadelphia Pennsylvania 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USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23079"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.09.67"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40675-020-00186-8"},{"issue":"5","key":"e_1_2_9_5_1","first-page":"930","article-title":"Central sleep apnoea\u2014a clinical review","volume":"7","author":"Muza RT","year":"2015","journal-title":"J Thorac 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