{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:09:06Z","timestamp":1791893346740,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T00:00:00Z","timestamp":1736035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Identify common pathogens and antibiotic resistances in chronic rhinosinusitis patients post\u2010endoscopic sinus surgery presenting with an active sinus infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single\u2010institution rhinology private practice in Southeast Florida.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Recorded postoperative endoscopically\u2010guided sinus cultures from symptomatic patients with purulent drainage on endoscopy from August 2020 to December 2023. When available, pre\u2010 or intraoperatively cultured organisms were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 125 patients, 50.4% were female with a mean age of 51.0. In 34.4% of patients that underwent revision surgery, 76% had nasal polyps and 26.4% had asthma. Of 301 cultures, 264 (87.7%) were positive, 53 (17.6%) were polymicrobial, and 37 (12.3%) were negative. Of 351 total isolates, 165 (47%) were Gram\u2010negative, 125 (35.6%) Gram\u2010positive, 14 (4%) fungi, and 10 (2.8%) anaerobic. 46.9% of postoperative organisms were not cultured preoperatively. Gram\u2010negative bacteria included Enterobacteriaceae (17.7%), <jats:italic>Pseudomonas<\/jats:italic> spp. (10.5%), <jats:italic>Serratia<\/jats:italic> spp. (5.1%). Gram\u2010positive bacteria included Methicillin\u2010sensitive <jats:italic>Staphylococcus aureus<\/jats:italic> (MSSA, 17.1%) and Methicillin\u2010resistant <jats:italic>S. aureus<\/jats:italic> (MRSA, 8%). Antibiotic resistances included MSSA to penicillins (52.8%) and clindamycin (32.8%), and MRSA resistance to quinolones (53.6%) and clindamycin (35.7%). Enterobacteriaceae were 42% resistant to amoxicillin\u2010clavulanate and 37.1% to penicillins, while <jats:italic>Pseudomonas aeruginosa<\/jats:italic> was 17.7% resistant to quinolones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A cohort of chronic rhinosinusitis patients post\u2010sinus surgery grew a large proportion of Gram\u2010negative organisms and significant <jats:italic>Staphylococcal<\/jats:italic> penicillin and Gram\u2010negative amoxicillin\u2010clavulanate resistance. Our findings indicate the benefit of culturing patients with this patient presentation. If cultures cannot be obtained, we suggest broad\u2010spectrum antibiotics that consider wide Gram\u2010negative coverage and local antibiotic resistance patterns.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.1122","type":"journal-article","created":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T12:04:25Z","timestamp":1736078665000},"page":"1442-1449","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Microbiological Profiles and Patterns of Resistance in Patients With Sinus Infections After Endoscopic Sinus Surgery"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0577-1635","authenticated-orcid":false,"given":"Avraham E.","family":"Adelman","sequence":"first","affiliation":[{"name":"Department of Surgery Schmidt College of Medicine Florida Atlantic University Boca Raton Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4010-6155","authenticated-orcid":false,"given":"Akshay","family":"Tangutur","sequence":"additional","affiliation":[{"name":"Department of Surgery Schmidt College of Medicine Florida Atlantic University Boca Raton Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo S.","family":"Archilla","sequence":"additional","affiliation":[{"name":"Department of Surgery Schmidt College of Medicine Florida Atlantic University Boca Raton Florida USA"},{"name":"ENT Specialists Boynton Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennadiy","family":"Vengerovich","sequence":"additional","affiliation":[{"name":"Department of Surgery Schmidt College of Medicine Florida Atlantic University Boca Raton Florida USA"},{"name":"ENT Specialists Boynton Beach Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,5]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"500","article-title":"Chronic rhinosinusitis","volume":"96","author":"Sedaghat AR","year":"2017","journal-title":"Am Fam Physician"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3981"},{"key":"e_1_2_8_4_1","first-page":"63","article-title":"Functional endoscopic sinus surgery. 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