{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:56:42Z","timestamp":1787313402614,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>High\u2010pitched voice disorders can present notable social and professional obstacles for cisgender and transgender men. Our study aims to conduct a comprehensive meta\u2010analysis assessing the efficacy of type III thyroplasty, also known as relaxation thyroplasty, for different populations with high\u2010pitched voice disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>A systematic literature review was conducted following Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses guidelines, searching Medline\/Pubmed, Embase, Cochrane, Science Direct, Scielo, LILACS, and Google Scholar databases from inception to April 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>Studies included patients undergoing type III thyroplasty for high\u2010pitched voice disorders. The primary outcome was the change in fundamental frequency postintervention. Subgroup analyses compared the following: (1) cisgender versus transgender populations, (2) primary versus secondary causes of high\u2010pitched voice disorders, and (3) unilateral versus bilateral vertical stripe resection techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The initial search yielded 284 articles, 9 studies, including 69 unique patients, were included in the analysis. All studies provided level 4 evidence. Most patients were cisgender men with primary mutational dysphonia (66.7%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946). The meta\u2010analysis showed a significant reduction in fundamental frequency after surgery, with a mean difference of \u221275.9\u2009Hz (95% confidence interval [CI]: \u221291.5 to \u221260.3). Cisgender men and patients submitted to unilateral resection had higher preoperative fundamental frequency and showed a more pronounced reduction in fundamental frequency. There were no significant differences between primary and secondary mutational dysphonia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Type III thyroplasty effectively lowers vocal pitch in patients with high\u2010pitched voice disorders. The procedure is viable for both cisgender and transgender men, as well as for primary and secondary voice disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.1185","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T09:41:15Z","timestamp":1741686075000},"page":"1847-1855","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Type III Thyroplasty for Patients With High\u2010Pitched Voice Disorders: A Systematic Review and Meta\u2010analysis"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7234-0045","authenticated-orcid":false,"given":"Bruno Dalla Vecchia","family":"Vendramini","sequence":"first","affiliation":[{"name":"Federal University of S\u00e3o Jo\u00e3o del Rei S\u00e3o Jo\u00e3o del Rei Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9598-2526","authenticated-orcid":false,"given":"Lucas Marinho Siqueira","family":"Campos","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Federal University of Pernambuco (UFPE) Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8208-7714","authenticated-orcid":false,"given":"Bruno Teixeira","family":"de Moraes","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Federal University of Pernambuco (UFPE) Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4827-0056","authenticated-orcid":false,"given":"Silvio Jos\u00e9","family":"de Vasconcelos","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Federal University of Pernambuco (UFPE) Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0721-6088","authenticated-orcid":false,"given":"Mateus Morais","family":"Aires","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Federal University of Pernambuco (UFPE) Recife Pernambuco Brazil"},{"name":"Faculty of Medical Sciences, University of Pernambuco (UPE) Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941011900207"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-72992002000100023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-023-03837-8"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199008000-00009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100143099"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.12.1263"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820937675"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31201"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487409126379"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2013.05.001"},{"key":"e_1_2_8_12_1","unstructured":"Oxford Centre for Evidence\u2010Based Medicine.The Oxford 2011 Levels of Evidence. vol1. Oxford Centre for Evidence\u2010Based Medicine;2011."},{"key":"e_1_2_8_13_1","volume-title":"The Newcastle\u2010Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta\u2010Analyses","author":"Wells G","year":"2021"},{"key":"e_1_2_8_14_1","unstructured":"National Center for Biotechnology Information. Newcastle\u2010Ottawa quality assessment form for cohort studies. Accessed September 18 2024.https:\/\/www.ncbi.nlm.nih.gov\/books\/nbk115843\/bin\/appe-fm3.pdf"},{"issue":"11","key":"e_1_2_8_15_1","first-page":"9515","article-title":"Isshiki type III thyroplasty: analysis of pre\u2010 and postoperative fundamental frequency in 10 patients","volume":"74","author":"Carneiro CdG","year":"2008","journal-title":"Braz J Otolaryngol"},{"issue":"3","key":"e_1_2_8_16_1","first-page":"178","article-title":"Voice change in transsexuals","volume":"10","author":"Oates J","year":"1997","journal-title":"Venereology"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817751030"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.1185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:07:48Z","timestamp":1760965668000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/ohn.1185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,27]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/ohn.1185"],"URL":"https:\/\/doi.org\/10.1002\/ohn.1185","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,27]]},"assertion":[{"value":"2024-09-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}