{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:52:09Z","timestamp":1786978329007,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T00:00:00Z","timestamp":1741305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine changes in trends of the incidence and characteristics of pediatric complicated rhinosinusitis with respect to the coronavirus disease 2019 (COVID\u201019) pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single tertiary\u2010care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A review of patients who presented to St. Louis Children's Hospital (SLCH) with complicated rhinosinusitis from 2017 to 2022 was performed. Clinical and follow\u2010up data were analyzed in association with COVID\u201019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty\u2010three patients with complicated rhinosinusitis were identified and analyzed according to hospitalization before or after March 2020. No differences in demographic variables were found between the two groups. More patients had developmental comorbidities in the COVID\u201019 group (7 vs 1,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.049). More patients with intracranial complications (55% vs 45%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.48) and Pott's puffy tumor\u00a0(78% vs 22%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.13) were observed in the COVID\u201019 era group; however, this difference was not statistically significant. In the COVID\u201019 group, more patients were found to have\n                      <jats:italic>Streptococcus anginosus<\/jats:italic>\n                      growth in their surgical cultures (67% vs 33%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.03). The incidence of complicated sinusitis correlated with the incidence of all viral cases at SLCH, particularly in 2021 and 2022, and increased following COVID\u201019.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Trends in complicated sinusitis vary before and after the onset of the COVID\u201019 pandemic. There was an increase in complications of sinusitis due to\n                      <jats:italic>S. anginosus<\/jats:italic>\n                      species in the COVID\u201019 era and trends towards increased intracranial complications and Pott's puffy tumor. After an initial decrease, the incidence of complicated sinusitis per year increased following COVID\u201019.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.1196","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T11:46:45Z","timestamp":1741693605000},"page":"2090-2097","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Trends in Complications of Pediatric Rhinosinusitis Before and During the COVID\u201019 Era"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3039-8112","authenticated-orcid":false,"given":"Amrita N.","family":"Bhat","sequence":"first","affiliation":[{"name":"Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny","family":"Wang","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Yang","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Molter","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Dunsky","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maithilee","family":"Menezes","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith E. C.","family":"Lieu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Washington University School of Medicine in St. Louis St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894041130S502"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2014.06.003"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.01.020"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197009000-00007"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1071"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.722483"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/01676830.2020.1768560"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3171\/CASE22423"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3171\/2024.5.PEDS2433"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.578"},{"key":"e_1_2_7_12_1","unstructured":"Notice on the continuation of the national emergency concerning the coronavirus disease 2019 (COVID\u201019) Pandemic. The White House. February 10 2023. Accessed January 1 2025.https:\/\/www.whitehouse.gov\/briefing-room\/presidentialactions\/2023\/02\/10\/notice-on-the-continuation-of-the-nationalemergency-concerning-the-coronavirus-disease-2019-covid-19pandemic-3\/#:~:text=For"},{"key":"e_1_2_7_13_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2023"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-65977-z"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.862"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)32675-X"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70307-8"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.7573\/dic.2020-9-3"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000002362"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820926463"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.6.650"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002514"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000004346"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000004235"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.1196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:07:32Z","timestamp":1760965652000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/ohn.1196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,7]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/ohn.1196"],"URL":"https:\/\/doi.org\/10.1002\/ohn.1196","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,7]]},"assertion":[{"value":"2024-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}