{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:43:06Z","timestamp":1761007386127,"version":"build-2065373602"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess relations between M\u00e9ni\u00e8re's disease and suicidality, measured by suicidal ideation, suicidal behaviors, and death by suicide.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>CINAHL, Cochrane Library, PubMed, PsycINFO, and SCOPUS databases were searched from inception through July 2, 2024.<\/jats:p><\/jats:sec><jats:sec><jats:title>Review Methods<\/jats:title><jats:p>Observational studies related to suicidality in patients with M\u00e9ni\u00e8re's disease were included. Non\u2010English language papers, editorials, and studies on vestibular disorders not specified as M\u00e9ni\u00e8re's disease were excluded. The Risk Of Bias In Nonrandomized Studies\u2010of Exposure tool was used for cohort and qualitative studies, and the Joanna Briggs Institute critical appraisal checklist was used for case\u2010control studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four studies (n\u2009=\u2009168,566) were included in our review. Two cohort studies found significantly increased adjusted hazard ratios of 2.1 (95% CI: 2.0\u20102.2) for death by suicide and 7.6 (95% CI: 4.4\u201013.3) for suicidal behaviors, respectively, in patients with M\u00e9ni\u00e8re's disease compared to the control population after their diagnosis. However, a case\u2010control study found no significant difference in the prevalence of suicidal ideation or behaviors prior to the date of diagnosis in patients with M\u00e9ni\u00e8re's disease compared to the control population (0.9% vs 0.8%; <jats:italic>P<\/jats:italic>\u2009=\u2009.44). In addition, one patient with M\u00e9ni\u00e8re's disease expressed suicidal ideation in the qualitative study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients may experience variable responses to M\u00e9ni\u00e8re's disease. Thus, otolaryngologists should be mindful of the potential for suicidality in patients with M\u00e9ni\u00e8re's disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.1216","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T21:01:21Z","timestamp":1741726881000},"page":"1866-1873","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Suicidal Ideation, Behaviors, and Deaths in People With M\u00e9ni\u00e8re's Disease: A Systematic Review"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2700-2721","authenticated-orcid":false,"given":"Lauren R.","family":"McCray","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Medical University of South Carolina Charleston South Carolina USA"},{"name":"Baylor College of Medicine Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah 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