{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T06:10:48Z","timestamp":1777097448837,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to evaluate the long\u2010term auditory performance at 5 years in patients with far advanced otosclerosis (FAO) after cochlear implantation compared to controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>This study was conducted at a single tertiary medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with FAO were compared to a control group of postlingually deafened patients, selected from the same cochlear implant database. The following data were collected from medical records: age, sex, etiology, duration of hearing deprivation, prior stapes surgery, age at implantation, side of implantation, computed tomography scan findings, surgery details, postoperative complications, and hearing test results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 41 patients with otosclerosis and 73 control cases were included in this study. The mean speech comprehension score at 5 years was 48.63%\u2009\u00b1\u200924.66 in the otosclerosis group compared to 48.17%\u2009\u00b1\u200923.08 in the control group (<jats:italic>P<\/jats:italic>\u2009=\u2009.76). Cochleostomy (<jats:italic>P<\/jats:italic>\u2009=\u2009.01), scala vestibuli insertion (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and postoperative dizziness (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) were more common in the otosclerosis group. Facial nerve stimulation was observed in both groups: otosclerosis group 4 cases (9.8%) and control group 4 cases (5.48%) (<jats:italic>P<\/jats:italic>\u2009=\u2009.39).<\/jats:p><jats:p>In the otosclerosis group, at 5 years, the average speech comprehension in patients with a previous stapedotomy was 39.3%\u2009\u00b1\u200923.9 and 57.52%\u2009\u00b1\u200922.45 in patients without a previous stapedotomy (<jats:italic>P<\/jats:italic>\u2009=\u2009.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cochlear\u2010implanted patients with otosclerosis achieve satisfactory long\u2010term audiometric outcomes, although with higher surgical challenges and complication rates compared to other etiologies. Notably, we found that a history of stapedotomy can negatively impact long\u2010term auditory outcomes after cochlear implantation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.1224","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T09:50:50Z","timestamp":1742377850000},"page":"2065-2071","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Long\u2010Term Hearing Outcomes Following Cochlear Implantation in Far Advanced Otosclerosis"],"prefix":"10.1002","volume":"172","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3877-121X","authenticated-orcid":false,"given":"Rapha\u00eble","family":"Quatre","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery University Hospital Grenoble Alpes France"},{"name":"GeodAIsics, Biopolis La Tronche France"},{"name":"BrainTech Lab, INSERM Unit 1205 Grenoble Alpes University Saint Martin D'H\u00e8re France"},{"name":"Department of CLINTEC, Division of Otorhinolaryngology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Ekl\u00f6f","sequence":"additional","affiliation":[{"name":"Department of CLINTEC, Division of Otorhinolaryngology Karolinska Institutet Stockholm Sweden"},{"name":"Medical Unit of ENT, Hearing and Balance Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Wales","sequence":"additional","affiliation":[{"name":"Department of CLINTEC, Division of Otorhinolaryngology Karolinska Institutet Stockholm Sweden"},{"name":"Medical Unit of ENT, Hearing and Balance Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5sa","family":"Bonnard","sequence":"additional","affiliation":[{"name":"Department of CLINTEC, Division of Otorhinolaryngology Karolinska Institutet Stockholm Sweden"},{"name":"Medical Unit of ENT, Hearing and Balance Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200103000-00023"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001552"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-07036-5"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-1442"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2014.03.011"},{"issue":"4","key":"e_1_2_9_7_1","first-page":"536","article-title":"Mixed hearing loss in otosclerosis: indication for long\u2010term follow\u2010up","volume":"15","author":"Ramsay HA","year":"1994","journal-title":"Am J 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