{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:31:07Z","timestamp":1784593867016,"version":"3.55.0"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Low\u2010grade parotid malignancies have high overall survival rates; however, controversy remains about the appropriate extent of surgery. We aim to explore the trends in the extent of parotidectomy performed over time in low\u2010grade parotid malignancies in the United States, with a hypothesis that there has been a trend towards less aggressive surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective cohort study of all low\u2010grade (grade I) acinic cell carcinoma (ACC) and mucoepidermoid carcinoma (MEC) in the Surveillance, Epidemiology, and End Results (SEER) from 2004 to 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Geographic areas served by SEER.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Trends were assessed using Cochran\u2010Armitage tests and logistic regression; Kaplan\u2010Meier survival curves were used to analyze overall and cancer\u2010specific survival, and chi\u2010square tests were used to analyze patient characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1288 patients were identified (916 MEC; 372 ACC). Most patients (n\u2009=\u2009772, 60%) were non\u2010Hispanic white, with an average age of 50.6 years and had a slight female predominance (1.58:1). Most of the cohort presented with tumor stage T1 or T2 (84%), N0 (90.1%), and M0 (96.9%). Treatment with total parotidectomy decreased significantly (34.6 vs 17.7%, <jats:italic>P<\/jats:italic>\u2009=\u2009.02) whereas sacrificing the facial nerve (FN) slightly decreased (20 vs 15.7%, <jats:italic>P<\/jats:italic>\u2009=\u2009.1). A significant increase in N0 patients (71%\u201094%, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.0001) was observed, whereas T staging remained stable (61%\u201064%, <jats:italic>P<\/jats:italic>\u2009=\u2009.3). Overall, both ACC and MEC had excellent cancer\u2010specific survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Over the last 17 years, there has been a significant de\u2010escalation in the extent of parotidectomy for low\u2010grade parotid malignancy in the United States.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.1305","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T06:45:44Z","timestamp":1747809944000},"page":"671-680","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Trends in the Extent of Surgical Management for Low\u2010Grade Parotid Malignancies: A SEER Analysis"],"prefix":"10.1002","volume":"173","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4329-5429","authenticated-orcid":false,"given":"Katelyn S.","family":"Rourk","sequence":"first","affiliation":[{"name":"Mayo Clinic Alix School of Medicine Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela A.","family":"Calcano","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawa M.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E.","family":"Glasgow","sequence":"additional","affiliation":[{"name":"Mayo Clinic Robert D. and Patricia E. 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Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8515-2051","authenticated-orcid":false,"given":"Linda X.","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"9","article-title":"Frequency and histopathology by site, major pathologies, symptoms and signs of salivary gland neoplasms","volume":"78","author":"Bradley PJ","year":"2016","journal-title":"Adv 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