{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:44:32Z","timestamp":1790837072178,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The platelet\u2010rich plasma (PRP) injection into the olfactory clefts has been suggested as an effective treatment for long\u2010lasting post\u2010viral olfactory dysfunction (OD). Currently, no prospective clinical studies have been conducted in other OD etiologies. In this preliminary study, the PRP injection outcomes were investigated in 33 posttraumatic OD patients (19 females; mean duration: 55.6\u2009\u00b1\u200945.1 months), and olfactory outcomes were compared with those of patients adhering to an olfactory training (OT). Following PRP injection, 66.7% of posttraumatic patients reported subjective improvement. Threshold, discrimination, and identification (TDI) scores significantly increased in both groups, achieving a minimal clinically important difference only in posttraumatic injected patients. In the posttraumatic group, the baseline TDI (8.4\u2009\u00b1\u20098.1) significantly increased at the 3\u2010month posttreatment (16.5\u2009\u00b1\u20099.6;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u2009.003). The 3\u2010month TDI score was significantly higher in posttraumatic injected patients versus OT patients (16.5\u2009\u00b1\u20099.6 vs 13.3\u2009\u00b1\u20098.5;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u2009.038). PRP injection can be an option for posttraumatic OD patients to improve olfactory recovery.\n                  <\/jats:p>","DOI":"10.1002\/ohn.1358","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T11:19:33Z","timestamp":1753183173000},"page":"1297-1301","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Platelet\u2010Rich Plasma for Posttraumatic Olfactory Dysfunction: Preliminary Report of 33 Patients"],"prefix":"10.1002","volume":"173","author":[{"given":"Jerome R.","family":"Lechien","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Polyclinic of Poitiers Elsan Poitiers France"},{"name":"Department of Surgery, UMONS Research Institute for Health Sciences and Technology, Faculty of Medicine University of Mons (UMons) Mons Belgium"},{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil Universit\u00e9 Versailles Saint\u2010Quentin\u2010en\u2010Yvelines (Paris Saclay University) Paris France"},{"name":"Department of Otorhinolaryngology and Head and Neck Surgery CHU Saint\u2010Pierre Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.357"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23116"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.1149"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-024-08816-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0173-0"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-022-00598-2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06810-9"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.460"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22135"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino11.141"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.05.232"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22758"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-83621-2"},{"issue":"13","key":"e_1_2_9_15_1","first-page":"97","article-title":"Posttraumatic olfactory dysfunction: a cohort study and update","volume":"5","author":"Collet S","year":"2009","journal-title":"B\u2010ENT"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1193406"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.1358","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ohn.1358","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.1358","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:15:02Z","timestamp":1790244902000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/ohn.1358"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,22]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/ohn.1358"],"URL":"https:\/\/doi.org\/10.1002\/ohn.1358","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,22]]},"assertion":[{"value":"2025-02-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}