{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:48:02Z","timestamp":1790390882886,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T00:00:00Z","timestamp":1674950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Upper airway stimulation (UAS) therapy has become increasingly utilized to treat obstructive sleep apnea, which is an independent risk factor for the development of hypertension. This study examines the impact of this therapy on blood pressure (BP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective cross\u2010sectional cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary center, Military Health System.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent UAS implantation at Brooke Army Medical Center between July 2015 and July 2020 were included if they used their device for at least 25\u2009h\/wk. Pre\u2010 and postoperative systolic BP, diastolic blood pressure (DBP), calculated mean arterial pressure (MAP), and the apnea\u2010hypopnea index (AHI) were compared using paired <jats:italic>t<\/jats:italic>\u00a0test or Wilcoxon's signed\u2010rank test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty patients met the inclusion criteria. The median age was 60, and the median body mass index was 29.9\u2009kg\/m<jats:sup>2<\/jats:sup>. The mean time between pre\u2010 and postoperative BP measurements was 11.6 months. AHI decreased from 35.1\u00a0to 16.5\u2009events\/h\u00a0(<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). DBP decreased from 78.5\u2009(73.8, 85.0) to 74.5\u2009mm\u2009Hg (68.8, 81.3), with a mean difference of \u22123.7\u2009mm\u2009Hg (<jats:italic>p<\/jats:italic>\u2009=\u2009.002). MAP decreased from 94.8 (89.6, 100.6) to 90.2\u2009mm\u2009Hg (84.3, 100.0), with a mean difference of \u22123.7\u2009mm\u2009Hg (<jats:italic>p<\/jats:italic>\u2009=\u2009.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>UAS therapy was associated with a significant reduction in DBP, MAP, and AHI. These reductions in BP could potentially lead to favorable decreases in cardiovascular morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.210","type":"journal-article","created":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T11:29:15Z","timestamp":1674991755000},"page":"1551-1556","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Upper Airway Stimulation Therapy Effect on Blood Pressure"],"prefix":"10.1002","volume":"168","author":[{"given":"Alex J.","family":"McKinlay","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Brooke Army Medical Center San Antonio Texas USA"},{"name":"Sleep Disorders Center, Wilford Hall Ambulatory Surgical Center San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6952-6869","authenticated-orcid":false,"given":"Benjamin 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