{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:46:44Z","timestamp":1761007604916,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T00:00:00Z","timestamp":1674604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the feasibility, characteristics, and outcomes of ultrasound\u2010guided ethanol ablation (US\u2010EA) as a primary treatment for thyroglossal duct cysts (TGDCs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single center study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The inclusion criteria were as follows: (i) patients with TGDC aged \u226518 years, (ii) benign TGDC in imaging and cytological examinations, and (iii) patients' need\u00a0for nonsurgical scarless treatment. US\u2010EA was used as the primary treatment strategy. The primary outcome variables were the volume reduction rate (VRR) and cosmetic score at the last follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We enrolled 28 patients with TGDC. The median TGDC volume at baseline was 6.7\u2009mL. The median procedure time of the US\u2010EA was 6.5 minutes. The median volumes of the cyst aspirate and injected ethanol were 4.0 and 2.0\u2009mL, respectively. Overall, 18, 8, and 2 patients underwent 1, 2, and 3 treatment sessions, respectively. There were no complications. The median VRR was 96.2%, and the treatment success rate was 96.4%. The World Health Organization cosmetic score decreased from 4 (baseline) to 1 (after treatment) in all patients. The subjective grade for cosmetic satisfaction was satisfactory or highly satisfactory in all patients. The VRR, treatment success rate, and the number of treatment sessions did not differ as functions of the characteristics of the TGDC, including the initial volume, septation, debris, or viscosity of the cyst fluid.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>US\u2010EA was feasible, safe, and effective in patients with TGDC. Therefore, US\u2010EA can be used as a primary treatment for TGDC, evading general anesthesia and surgical scar.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.231","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T06:54:15Z","timestamp":1674629655000},"page":"1381-1388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ultrasound\u2010Guided Ethanol Ablation as a Primary Treatment for Thyroglossal Duct Cyst: Feasibility, Characteristics, and Outcomes"],"prefix":"10.1002","volume":"168","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4977-7406","authenticated-orcid":false,"given":"Dongbin","family":"Ahn","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, School of Medicine Kyungpook National University  Daegu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji 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