{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:02:50Z","timestamp":1789704170347,"version":"4.0.1"},"reference-count":61,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Audiometric outcomes at 12 months following simultaneous translabyrinthine (TL) resection of vestibular schwannoma (VS) and cochlear implantation (CI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary referral center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adult patients undergoing TL resection of sporadic, unilateral VS\u2009\u2264\u20092\u2009cm were prospectively enrolled. Preoperative testing included binaural AZBio in noise and quiet and unilateral Consonant\u2010Nucleus\u2010Consonant (CNC). Tinnitus Handicap Index (THI) and Speech, Spatial, and Qualities of Hearing (SSQ) questionnaires were also completed. Patients underwent TL resection with simultaneous CI. The preoperative test battery was repeated at 1, 3, 6, and 12 months after activation. Statistical analysis was performed to characterize short\u2010term outcomes (preoperative to 3 months), longer\u2010term outcomes (3\u201012 months), and overall changes during the preoperative to 12\u2010month period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AZBio, CNC, and THI improved at 3 months with no significant changes thereafter and showed durable improvement at 12 months compared to preoperative testing. While SSQ did not improve at 12 months, a subset of patients showed either recovery or improvement of SSQ\u2010spatial subscores. Patients with cerebellopontine angle tumors had poorer performance, although the impact of tumor size and location could not be deduced based on the small sample size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients undergoing simultaneous CI and TL resection of VS had durable improvements in speech perception and tinnitus severity 12 months following surgery. Subjective improvements in localization were not observed. Additional studies are needed to determine which VS patients are optimal candidates for CI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.261","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T01:20:08Z","timestamp":1675128008000},"page":"358-366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Twelve\u2010Month Outcomes of Simultaneous Translabyrinthine Resection and Cochlear Implantation"],"prefix":"10.1002","volume":"169","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9409-4946","authenticated-orcid":false,"given":"Karl W.","family":"Doerfer","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Communication Sciences Medical College of Wisconsin  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3821-3859","authenticated-orcid":false,"given":"Christian G.","family":"Fritz","sequence":"additional","affiliation":[{"name":"Division of Neurotologic and Lateral Skull Base Surgery Michigan Ear Institute  Farmington Hills Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8858-2241","authenticated-orcid":false,"given":"Sandra L.","family":"Porps","sequence":"additional","affiliation":[{"name":"Division of Neurotologic and Lateral Skull Base Surgery Michigan Ear Institute  Farmington Hills Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4861-9358","authenticated-orcid":false,"given":"Robert S.","family":"Hong","sequence":"additional","affiliation":[{"name":"Division of Neurotologic and Lateral Skull Base Surgery Michigan Ear Institute  Farmington Hills Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7793-7411","authenticated-orcid":false,"given":"Jeffrey T.","family":"Jacob","sequence":"additional","affiliation":[{"name":"Division of Skull Base Surgery Michigan Head and Spine Institute  Southfield Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8670-8792","authenticated-orcid":false,"given":"Seilesh C.","family":"Babu","sequence":"additional","affiliation":[{"name":"Division of Neurotologic and Lateral Skull Base Surgery Michigan Ear Institute  Farmington Hills Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000244186.72645.d4"},{"key":"e_1_2_8_3_1","first-page":"110","article-title":"Management of 1000 vestibular schwannomas (acoustic neuromas): clinical presentation","volume":"40","author":"Matthies C","year":"1993","journal-title":"Neurosurgery"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1288\/00005537-198902000-00010","article-title":"Acoustic neuroma, the patient's perspective: subjective assessment of symptoms, diagnosis, therapy, and outcome in 541 patients","volume":"99","author":"Wiegand DA","year":"1989","journal-title":"Laryngoscope"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310000647"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.11.JNS14594"},{"key":"e_1_2_8_7_1","article-title":"Signs and symptoms of acoustic neuroma at initial presentation: an exploratory analysis","volume":"9","author":"Foley RW","year":"2017","journal-title":"Cureus"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000760"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000329362"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e3283579673"},{"issue":"2","key":"e_1_2_8_11_1","first-page":"76","article-title":"Hearing preservation surgery in acoustic neuroma. 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