{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:02:29Z","timestamp":1789704149938,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T00:00:00Z","timestamp":1675728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T00:00:00Z","timestamp":1675728000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,8]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n The optimal management of acute mastoiditis remains controversial. Most existing studies are retrospective single\u2010institutional experiences with small cohorts. Our objectives were to analyze the treatment of acute mastoiditis by pediatric centers across the United States and changes in management over time.<\/jats:p>\n <\/jats:sec>\n \n Study Design<\/jats:title>\n Retrospective analysis.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Administrative database study using Pediatric Health Information System.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Patients \u226418 years of age who were admitted with a principal diagnosis of acute mastoiditis from January 1, 2010 to December 31, 2019 were included. Trends were assessed by Cochran\u2010Armitage Trend Test.\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n and Wilcoxon rank sum tests were used to compare outcomes between the surgical and nonsurgical groups.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 2170 patients met the inclusion criteria, with 1248 (57.5%) requiring surgical management. The rate of surgical procedures decreased significantly over time. The rate of myringotomy decreased from 64% in 2010 to 47% in 2019 (\n p<\/jats:italic>\n \u2009<\u2009.001), and mastoidectomy decreased from 22% in 2010 to 10% in 2019 (\n p<\/jats:italic>\n \u2009<\u2009.001). On admission, 29% of the cohort presented with mastoiditis\u2010related complications. Patients treated surgically were younger (\n p<\/jats:italic>\n \u2009<\u2009.001), more likely to present with complications (37.5% vs 17.5%,\n p<\/jats:italic>\n \u2009<\u2009.001), required longer length\u00a0of stay (3.7\u00a0vs 2.3 days,\n p<\/jats:italic>\n \u2009<\u2009.001), and had higher intensive care unit utilization (8.6% vs 2.2%,\n p<\/jats:italic>\n \u2009<\u2009.001). However, the rate of 30\u2010day readmission, emergency department return, and in\u2010hospital mortality were all similar.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Acute mastoiditis has been successfully treated with declining rates of a surgery over time. Younger patients who present with complications are more likely to be managed surgically, and the overall outcomes remain excellent.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ohn.286","type":"journal-article","created":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T07:46:22Z","timestamp":1675755982000},"page":"382-389","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Evolving Management of Acute Mastoiditis: Analysis of the Pediatric Health Information System Database"],"prefix":"10.1002","volume":"169","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1879-4868","authenticated-orcid":false,"given":"Tzyynong L.","family":"Friesen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of California San Diego San Diego California USA"},{"name":"Division of Otolaryngology Rady Children's Hospital San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt","family":"Hall","sequence":"additional","affiliation":[{"name":"Children's Hospital Association Lenexa Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2982-8031","authenticated-orcid":false,"given":"Nanda","family":"Ramchandar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Naval Medical Center San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3917-4465","authenticated-orcid":false,"given":"Jay G.","family":"Berry","sequence":"additional","affiliation":[{"name":"Division of General Pediatrics Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of California San Diego San Diego California 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