{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:56:36Z","timestamp":1788857796887,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T00:00:00Z","timestamp":1677715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Assessment of recovery following vestibular loss has been limited by the lack of bedside measures in clinical settings. Here, we used the video ocular counter\u2010roll (vOCR) test to study otolith\u2010ocular function and compensatory effect of neck proprioception in patients at different stages of vestibular loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Case\u2010control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010six subjects were recruited including patients with acute (9\u2009\u00b1\u20092 days [mean\u2009\u00b1\u2009standard error of mean]), subacute (61\u2009\u00b1\u200911 days), and chronic (1009\u2009\u00b1\u2009266 days) unilateral loss of vestibular function, as well as a group of healthy controls. We used a video\u2010oculography method based on tracking the iris for vOCR measurement. To examine the effect of neck inputs, vOCR was recorded during two simple tilt maneuvers in all subjects while seated: 30\u00b0\u00a0head\u2010on\u2010body tilt and 30\u00b0\u00a0head\u2010and\u2010body tilt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The vOCR responses evolved at different stages following vestibular loss with improvement of the gains in the chronic stage. The deficit was more pronounced when the whole body was tilted (acute: 0.08\u2009\u00b1\u20090.01, subacute: 0.11\u2009\u00b1\u20090.01, chronic: 0.13\u2009\u00b1\u20090.02, healthy control: 0.18\u2009\u00b1\u20090.01), and the gain of vOCR improved when the head was tilted on the body (acute: 0.11\u2009\u00b1\u20090.01, subacute: 0.14\u2009\u00b1\u20090.01, chronic: 0.13\u2009\u00b1\u20090.02, healthy control: 0.17\u2009\u00b1\u20090.01). The time course of vOCR response was affected as well with reduced amplitude and slower response in the acute stage of vestibular loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The vOCR test can be valuable as a clinical marker to measure vestibular recovery and compensatory effect of neck proprioception in patients at different stages following loss of vestibular function.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.304","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T07:18:10Z","timestamp":1677741490000},"page":"660-669","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Video Ocular Counter\u2010Roll (vOCR): Otolith\u2010Ocular Function and Compensatory Effect of the Neck Following Vestibular Loss"],"prefix":"10.1002","volume":"169","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9004-8638","authenticated-orcid":false,"given":"Yuchen","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Neurology The Johns Hopkins University School of Medicine Baltimore Maryland USA"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery The Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Neurology The Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Otero\u2010Millan","sequence":"additional","affiliation":[{"name":"Department of Neurology The Johns Hopkins University School of Medicine Baltimore Maryland USA"},{"name":"Herbert Wertheim School of Optometry and Vision Science University of California  Berkeley California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Schubert","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery The Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"Department of Physical Medicine and Rehabilitation The Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3630-3949","authenticated-orcid":false,"given":"Amir","family":"Kheradmand","sequence":"additional","affiliation":[{"name":"Department of Neurology The Johns Hopkins University School of Medicine Baltimore Maryland USA"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery The Johns Hopkins University School of Medicine  Baltimore Maryland 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