{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T02:44:20Z","timestamp":1767840260235,"version":"3.49.0"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T00:00:00Z","timestamp":1692316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study examines the trends in the management of thyroid cancer and clinical outcomes in the Southwestern region of The Netherlands from 2010 to 2021, where a regional collaborative network has been implemented in January 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>This study encompasses all patients diagnosed with thyroid cancer of any subtype between January 2010 and June 2021 in 10 collaborating hospitals in the Southwestern region of The Netherlands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The primary outcome of this study was the occurrence of postoperative complications. Secondary outcomes were trends in surgical management, centralization, and waiting times of patients with thyroid cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 1186 patients with thyroid cancer. Median follow\u2010up was 58 [interquartile range: 24\u201095] months. Surgery was performed in 1027 (86.6%) patients. No differences in postoperative complications, such as long\u2010term hypoparathyroidism, permanent recurrent nerve paresis, or reoperation due to bleeding were seen over time. The percentage of patients with low\u2010risk papillary thyroid carcinoma referred to the academic hospital decreased from 85% (n\u2009=\u2009120\/142) in 2010 to 2013 to 70% (n\u2009=\u2009120\/171) in 2014 to 2017 and 62% (n\u2009=\u2009100\/162) in 2018 to 2021 (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). The percentage of patients undergoing a hemithyroidectomy alone was 9% (n\u2009=\u200928\/323) in 2010 to 2013 and increased to 20% (n\u2009=\u200963\/317; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) in 2018 to 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The establishment of a regional oncological network coincided with a de\u2010escalation of thyroid cancer treatment and centralization of complex patients and interventions. However, no differences in postoperative complications over time were observed. Determining the impact of regional oncological networks on quality of care is challenging in the absence of uniform quality indicators.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.481","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T15:53:51Z","timestamp":1692633231000},"page":"159-168","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Regional Collaboration and Trends in Clinical Management of Thyroid Cancer"],"prefix":"10.1002","volume":"170","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4745-7978","authenticated-orcid":false,"given":"Sam P.J.","family":"van Dijk","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannelore I.","family":"Coerts","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivona","family":"Lon\u010dar","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline M.J.","family":"van Kinschot","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Erasmus Medical Centre Rotterdam Rotterdam The Netherlands"},{"name":"Department of Internal Medicine Maasstad Hospital Rotterdam Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik M.","family":"von Meyenfeldt","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology Albert Schweitzer Hospital Dordrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Edward Visser","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Erasmus Medical Centre Rotterdam Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"van Noord","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Maasstad Hospital Rotterdam Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans F.","family":"Zengerink","sequence":"additional","affiliation":[{"name":"Department of Surgery Franciscus Gasthuis &amp; Vlietland Rotterdam Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc R.J.","family":"ten Broek","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Reinier de Graaf Hospital Delft Delft The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelis","family":"Verhoef","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin P.","family":"Peeters","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Erasmus Medical Centre Rotterdam Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tessa M.","family":"van Ginhoven","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,18]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"238","volume-title":"Building Regional Health Care Networks in Europe","author":"Oates J","year":"2000"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23844"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2013.05.010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e31824ebe13"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29028"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2013.001268"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2012.000598"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2012.08.008"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/01945998221086203"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2015.03.029"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2014.01.006"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckr153"},{"key":"e_1_2_10_14_1","unstructured":"De Juiste Zorg op de Juiste Plek.Taskforce report: the right care in the right place. 2018. Accessed May 13 2023.https:\/\/www.dejuistezorgopdejuisteplek.nl\/.uc\/fcef77d2b01028d5c0000bd7ca7026baaac90942d76c900\/The%20right%20care%20in%20the%20right%20place_report%20taskforce.pdf"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD"},{"issue":"4","key":"e_1_2_10_16_1","first-page":"14","article-title":"What works? Waiting time policies in the health sector","volume":"21","author":"Siciliani L","year":"2015","journal-title":"Eurohealth"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-21-1044"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-88441-7"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2015.0020"},{"key":"e_1_2_10_20_1","unstructured":"LinksT.Richtlijn voor de diagnostiek behandeling en follow\u2010up van pati\u00ebnten met gedifferentieerd (niet\u2010medullair) schildkliercarcinoom [pdf].2015. Accessed May 13 2023.https:\/\/www.nhg.org\/sites\/default\/files\/content\/nhg_org\/uploads\/schildkliercarcinoom.pdf"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2022.3360"},{"key":"e_1_2_10_22_1","doi-asserted-by":"crossref","unstructured":"GrahamRMM Miller WolmanD Institute of Medicine (US) Committee on Standards for Developing Trustworthy Clinical Practice Guidelines et al.Promoting Adoption of Clinical Practice Guidelines. National Academies Press; 2011.","DOI":"10.17226\/13058"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2019.10.006"},{"key":"e_1_2_10_24_1","unstructured":"Ministerie van Volksgezondheid Welzijn en Sport (VWS) en de NederlandseZorgautoriteit (NZa).Bestuurlijk Akkoord Plan van aanpak ROBIJN. VWS NZa;2017."},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa012337"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-00255"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2022.101859"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-017-5833-3"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajco.12192"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-020-4930-3"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2015.11.007"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2017.07.023"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S220976"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-2957-y"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgad163"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2021.2475"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-019-02014-8"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003800"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2013.04.003"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13012-016-0373-y"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02049-2015"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.08.075"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.4851"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/14737140.2016.1222274"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2010.00430.x"},{"issue":"7","key":"e_1_2_10_46_1","first-page":"206","article-title":"Use of a registry to improve acute stroke care\u2014seven states, 2005\u20102009","volume":"60","author":"Centers for Disease Control and Prevention (CDC)","year":"2011","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.3109\/02688697.2013.859657"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:45:25Z","timestamp":1760953525000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/ohn.481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,18]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/ohn.481"],"URL":"https:\/\/doi.org\/10.1002\/ohn.481","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,18]]},"assertion":[{"value":"2023-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}