{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T09:59:15Z","timestamp":1775037555620,"version":"3.50.1"},"reference-count":62,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the safety and efficacy of a novel active transcutaneous bone conduction implant (BCI) device for patients with single\u2010sided deafness (SSD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral hospitals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective multicenter study was conducted at 15 institutions nationwide. Thirty adult (aged \u226519 years) SSD patients were recruited. They underwent implantation of an active transcutaneous BCI device (Bonebridge BCI602). Objective outcomes included aided pure\u2010tone thresholds, aided speech discrimination scores (SDSs), and the Hearing in Noise Test (HINT) and sound localization test results. The Bern Benefit in Single\u2010Sided Deafness (BBSS) questionnaire, the Abbreviated Profile of Hearing Aid Benefit (APHAB) questionnaire, and the Tinnitus Handicap Inventory (THI) were used to measure subjective benefits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean aided pure\u2010tone threshold was 34.2 (11.3), mean (SD), dB HL at 500 to 4000\u2009Hz. The mean total BBSS score was 27.5 (13.8). All APHAB questionnaire domain scores showed significant improvements: ease of communication, 33.6 (23.2) versus 22.6 (21.3), <jats:italic>P<\/jats:italic>\u2009=\u2009.025; reverberation, 44.8 (16.6) versus 32.8 (15.9), <jats:italic>P<\/jats:italic>\u2009=\u2009.002; background noise, 55.5 (23.6) versus 35.2 (18.1), <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; and aversiveness, 36.7 (22.8) versus 25.8 (21.4), <jats:italic>P<\/jats:italic>\u2009=\u2009.028. Moreover, the THI scores were significantly reduced [47.4 (30.1) versus 31.1 (27.0), <jats:italic>P<\/jats:italic>\u2009=\u2009.003]. Congenital SSD was a significant factor of subjective benefit (\u221211.643; 95% confidence interval: \u221221.946 to \u22121.340).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The BCI602 active transcutaneous BCI device can provide functional hearing gain without any adverse effects and is a feasible option for acquired SSD patients with long\u2010term deafness.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.520","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:19:19Z","timestamp":1697059159000},"page":"490-504","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Efficacy of the Bonebridge BCI602 for Adult Patients with Single\u2010sided Deafness: A Prospective Multicenter 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