{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T09:52:30Z","timestamp":1789638750618,"version":"4.0.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the sensitivity and the specificity of summating potential (SP)\/action potential (AP) area under the curve (AUC) ratio by a transtympanic electrode and a click stimulus (TT\u2010CS), SP\/AP AUC ratio by an extratympanic electrode and a click stimulus (ET\u2010CS) and SP amplitude value by a transtympanic electrode and tone burst stimulus (TT\u2010TBS) in regard of M\u00e9ni\u00e8re's disease (MD) diagnosis. This is the first study that compares SP amplitude value performed by a TT\u2010TBS and the SP\/AP AUC ratio performed by a TT\u2010CS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Retrospective comparative study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Settings<\/jats:title><jats:p>Ninety\u2010five patients met the inclusion criteria for electrocochleography (ECochG) testing in a tertiary care center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The sensitivity and specificity of our different ECochG protocols were calculated in regard\u00a0of the diagnosis of MD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The patients' mean age was 54 years old (female predominance). The sensitivity and the specificity of SP\/AP area ratio by a TT\u2010CS were 88.5% and 70.0%, respectively. On the other hand, the sensitivity and specificity for the SP amplitude value by a TT\u2010TBS were 60.0% and 55.6%, respectively. SP\/AP area ratio by TT\u2010CS was statistically better than SP amplitude value by TT\u2010TBS to detect MD disease (<jats:italic>P\u2009<\/jats:italic>=\u2009.016). However, no difference was identified between SP\/AP area ratio by ET\u2010CS and SP amplitude value by a TT\u2010TBS (<jats:italic>P<\/jats:italic>\u2009=\u2009.573).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SP\/AP area ratio by click stimulation has higher sensitivity and specificity to detect MD compared to SP amplitude value by tone burst stimulation. ECochG would be extremely useful in the diagnosis of MD if we use the SP\/AP area ratio (sensitivity: 88.5%); therefore, it changes the bad reputation of ECochG sensitivity using SP\/AP amplitude ratio (sensitivity: 51.7%) for the diagnosis of MD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.693","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T07:43:16Z","timestamp":1709106196000},"page":"494-501","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Click SP\/AP Area Ratio Vesrus Tone Burst SP Amplitude to Diagnose M\u00e9ni\u00e8re's Disease Using Electrocochleography"],"prefix":"10.1002","volume":"171","author":[{"given":"Naif","family":"Bawazeer","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery University of Montreal Montreal Qu\u00e9bec 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