{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:31:55Z","timestamp":1786386715232,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study is to ascertain the rate of malignancy in nodules that are less than 10\u2009mm in diameter in the TR\u20104 and TR\u20105 categories, as defined by the American College of Radiology Thyroid Imaging and Reporting Data System 2017 whitepaper and to open a discussion on the strategy of approach to PTMCs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single academic medical center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All thyroid ultrasound examinations were performed by 2 senior radiologists with consensus. The fine\u2010needle aspiration biopsy procedure was performed under the guidance of ultrasound. All patients underwent surgery, except for those with benign cytology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 60 nodules, 15 nodules (25%) were classified as TR\u20104 and 45 nodules (75%) as TR\u20105. Based on cytological analysis, 12 of the 15 nodules classified in the TR\u20104 category (80%) were benign, while 3 nodules (20%) were classified as nonbenign. In the assessment of 45 TR\u20105 nodules, 30 (66.7%) were identified as nonbenign, while the remaining 15 (33.3%) were classified as benign. Surgery was performed on all 33 patients with nonbenign FNAB results, and the histopathological results confirmed malignancy in 3 TR\u20104 nodules (20%) and in 29 TR\u20105 nodules (64.4%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study highlights that TR\u20104 and TR\u20105 thyroid nodules smaller than 10\u2009mm exhibit high malignancy rates. Despite limitations such as small sample size and single\u2010center design, our findings support the consideration of FNAB in selected &lt;10\u2009mm nodules, particularly when active surveillance is unsuitable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.70084","type":"journal-article","created":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T17:06:39Z","timestamp":1765127199000},"page":"366-374","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Follow up or FNAB?: Malignancy Rates of ACR TI\u2010RADS 4 and 5 Thyroid Nodules &lt;10\u2009mm in Diameter"],"prefix":"10.1002","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0144-0142","authenticated-orcid":false,"given":"Eren","family":"Tobcu","sequence":"first","affiliation":[{"name":"Department of Radiology Band\u0131rma Onyedi Eylul University School of Medicine, Bal\u0131kesir, T\u00fcrkiye. Band\u0131rma Onyedi Eyl\u00fcl \u00dcniversitesi Merkez Yerle\u015fkesi Band\u0131rma 10200 Bal\u0131kesir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6649-3256","authenticated-orcid":false,"given":"Erdal","family":"Karava\u015f","sequence":"additional","affiliation":[{"name":"Department of Radiology Band\u0131rma Onyedi Eylul University School of Medicine, Bal\u0131kesir, T\u00fcrkiye. Band\u0131rma Onyedi Eyl\u00fcl \u00dcniversitesi Merkez Yerle\u015fkesi Band\u0131rma 10200 Bal\u0131kesir T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8921-3704","authenticated-orcid":false,"given":"G\u00fclden Ta\u015fova","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Department of Pathology Band\u0131rma Research and Training Hospital, Bal\u0131kesir, T\u00fcrkiye. 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