{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:31:56Z","timestamp":1786386716580,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Free jejunal transfers are a standard method for reconstruction after total pharyngolaryngectomy. However, the relative advantages of mechanical stapling compared to hand\u2010sewn techniques for cervical esophagojejunal anastomosis remain unclear. This study aimed to compare postoperative outcomes between these two approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary academic medical center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective review on 28 patients undergoing free jejunal transfer after total pharyngolaryngectomy between 2014 and 2020. Patients were divided into a mechanical stapler group (n\u2009=\u200912) and a hand\u2010sewn group (n\u2009=\u200916). Outcomes assessed included postoperative complications within 30 days and functional outcomes at or beyond 6 months postoperatively (mechanical stapler: n\u2009=\u20098; hand\u2010sewn: n\u2009=\u200910). We conducted statistical analysis using Fisher's exact and Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The overall incidence of early postoperative complications was similar between groups. Median operative time was significantly shorter with mechanical stapling (437 vs 540\u2009minutes;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.002). Functional outcomes, including oral intake and dysphagia symptoms, showed no significant differences. Nasal regurgitation was less frequent with stapling (37.5% vs 90%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.043). One anastomotic stricture occurred in the stapler group and we successfully treated it with two sessions of endoscopic balloon dilatation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Mechanical stapling provides comparable functional outcomes to hand\u2010sewn anastomosis while offering the advantage of shorter operative time. These findings support its use as a practical and efficient alternative for cervical esophagojejunal reconstruction following total pharyngolaryngectomy, particularly in settings seeking to optimize both efficiency and safety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>umin.ac.jp\/ctr Identifier: UMIN000057262.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\u2162.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.70090","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T13:24:25Z","timestamp":1765977865000},"page":"395-402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mechanical Stapling Versus Hand\u2010Sewn Technique for End\u2010to\u2010End Anastomosis in Free Jejunal Transfers Following Total Pharyngolaryngectomy"],"prefix":"10.1002","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7342-024X","authenticated-orcid":false,"given":"Haruyuki","family":"Hirayama","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4604-0847","authenticated-orcid":false,"given":"Katsuhiro","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3970-0770","authenticated-orcid":false,"given":"Hiroki","family":"Kodama","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4020-7618","authenticated-orcid":false,"given":"Doruk","family":"Orgun","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6745-8483","authenticated-orcid":false,"given":"Masaki","family":"Nukami","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasutaka","family":"Kudo","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3747-9883","authenticated-orcid":false,"given":"Tatsuya","family":"Ishizuka","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2209-5722","authenticated-orcid":false,"given":"Soichiro","family":"Fukuzato","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1901-6718","authenticated-orcid":false,"given":"Takeshi","family":"Miyawaki","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, The Jikei University School of Medicine, 3\u201025\u20108 Nishi\u2010shimbashi Minato\u2010ku Tokyo 105\u20108461 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27526"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/02844319850158651"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199001000-00004"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988709600206"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e31817439c5"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21806"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2015.42.6.815"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198111000-00014"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200007000-00031"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.11.049"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2004.02.026"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000034363"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2018.03.022"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181f446a6"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199511000-00012"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000200622.13312.d3"}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.70090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ohn.70090","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.70090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T18:26:50Z","timestamp":1786386410000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/ohn.70090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,17]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/ohn.70090"],"URL":"https:\/\/doi.org\/10.1002\/ohn.70090","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,17]]},"assertion":[{"value":"2025-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}