{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:17:24Z","timestamp":1777706244676,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify patterns in prophylactic intravenous antibiotics (PIAB) usage for thyroglossal duct and branchial cleft cyst excisions, and to evaluate whether PIAB improve patient outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>American College of Surgeons National Surgical Quality Improvement Program\u2010Pediatric (NSQIP\u2010P) Surgical Antibiotic Prophylaxis Database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The NSQIP\u2010P database was queried for pediatric patients (\u226418) from 2021 to 2023 who underwent thyroglossal duct or branchial cleft cyst excision. Multivariate regressions assessed associations between PIAB use and outcomes including surgical site infection, unplanned readmission, and reoperation while adjusting for clinicodemographic factors (age, sex, race\/ethnicity, admission status, surgical specialty, ASA classification, and wound classification).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 2106 TGDC and 2837 BCC patients, 83.5% and 68.0% received PIAB, respectively. Hispanic ethnicity, postoperative admission, and clean\u2010contaminated wound classification were associated with increased PIAB use in both groups. In BCC patients, younger age and treatment by non\u2010otolaryngologists predicted decreased PIAB use. While univariate analysis in TGDC cases showed lower infection rates with PIAB (OR, 0.52; 95% CI, 0.30\u20100.95;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.025), this was not significant on multivariate analysis (0.59, 0.34\u20101.08,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.074). PIAB did not significantly affect infection, readmission, or reoperation rates in either cohort on multivariate analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PIAB use in pediatric TGDC and BCC excisions varies with clinicodemographic factors but did not consistently reduce adverse outcomes. These findings underscore the need to reevaluate the necessity of PIAB and encourage further investigations to develop evidence\u2010based guidelines for pediatric neck mass surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.70186","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:37:19Z","timestamp":1772998639000},"page":"1243-1252","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prophylactic Intravenous Antibiotic Use in Thyroglossal Duct and Branchial Cleft Cyst Excision: A NSQIP\u2010P Analysis"],"prefix":"10.1002","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6359-5393","authenticated-orcid":false,"given":"Cyrus W.","family":"Abrahamson","sequence":"first","affiliation":[{"name":"Feinberg School of Medicine Northwestern University Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1653-3193","authenticated-orcid":false,"given":"Thomas Q.","family":"McClelland","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine Northwestern University Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4485-8274","authenticated-orcid":false,"given":"David J.","family":"Fei\u2010Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5894-0155","authenticated-orcid":false,"given":"Jill N.","family":"D'Souza","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Division of Pediatric Otolaryngology Children's Hospital of New Orleans Louisiana State University Health Sciences Center New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5924-3689","authenticated-orcid":false,"given":"Anthony M.","family":"Sheyn","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Tennessee Health Science Center Memphis Tennessee USA"},{"name":"Department of Pediatric Otolaryngology Le Bonheur Children's Hospital Memphis Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0168-549X","authenticated-orcid":false,"given":"Jeffrey C.","family":"Rastatter","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA"},{"name":"Division of Pediatric Otolaryngology Ann &amp; Robert H. Lurie Children's Hospital of Chicago Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2378-2522","authenticated-orcid":false,"given":"Daniel C.","family":"Chelius","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Baylor College of Medicine Houston Texas USA"},{"name":"Department of Surgery, Division of Pediatric Otolaryngology Texas Children's Hospital Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,3]]},"reference":[{"issue":"3","key":"e_1_2_9_2_1","first-page":"142","article-title":"Thyroglossal duct cysts and branchial cleft anomalies","volume":"3","author":"Roback SA","year":"1994","journal-title":"Semin Pediatr Surg"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.11.039"},{"key":"e_1_2_9_4_1","unstructured":"AmosJ SuttonAE ShermetaroC. 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American College of Surgeons; 2024."}],"container-title":["Otolaryngology\u2013Head and Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.70186","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ohn.70186","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ohn.70186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:46:23Z","timestamp":1777455983000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/ohn.70186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,3]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/ohn.70186"],"URL":"https:\/\/doi.org\/10.1002\/ohn.70186","archive":["Portico"],"relation":{},"ISSN":["0194-5998","1097-6817"],"issn-type":[{"value":"0194-5998","type":"print"},{"value":"1097-6817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,3]]},"assertion":[{"value":"2025-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}