{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T20:32:23Z","timestamp":1783197143536,"version":"3.54.6"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301330"],"award-info":[{"award-number":["82301330"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the optimal cut\u2010off value of the electrocochleography (ECochG) SP\/AP ratio and evaluate its correlation with endolymphatic hydrops (EH) in patients with unilateral M\u00e9ni\u00e8re's disease (MD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study enrolled 162 patients with unilateral MD. EH was assessed using gadolinium\u2010enhanced MRI, and ECochG was performed to measure the SP\/AP ratio. The correlation between SP\/AP and EH severity was analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean pure\u2010tone average (PTA) threshold was significantly higher in affected ears than in unaffected ears (51.0\u2009\u00b1\u200917.9\u2009dB vs 21.4\u2009\u00b1\u200910.6\u2009dB,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). The ECochG SP\/AP ratio was also elevated in affected ears (0.41\u2009\u00b1\u20090.17 vs 0.24\u2009\u00b1\u20090.12,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001) and showed significant correlations with cochlear (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.483,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001) and vestibular EH (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.476,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Receiver operating characteristic (ROC) analysis revealed an area under the curve (AUC) of 0.79 for distinguishing affected ears, with an optimal SP\/AP cut\u2010off value of 0.305 (sensitivity\u2009=\u200983.33%, specificity\u2009=\u200972.22%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The ECochG SP\/AP ratio demonstrates strong diagnostic utility for MD and correlates significantly with EH severity. A cut\u2010off value of 0.305 provides a reliable objective marker for early MD diagnosis and EH assessment, particularly in settings where MRI is unavailable. ECochG serves as a valuable adjunctive tool for clinical decision\u2010making in MD management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.70252","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T08:55:59Z","timestamp":1777280159000},"page":"198-205","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Correlation of Electrocochleography SP\/AP With Endolymphatic Hydrops in Unilateral M\u00e9ni\u00e8res Disease"],"prefix":"10.1002","volume":"175","author":[{"given":"Wenting","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Sun Yat\u2010Sen Memorial Hospital Sun Yat\u2010Sen University Guangzhou 510120 Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuangzhuang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Sun Yat\u2010Sen Memorial Hospital Sun Yat\u2010Sen University Guangzhou 510120 Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowu","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Sun Yat\u2010Sen Memorial Hospital Sun Yat\u2010Sen University Guangzhou 510120 Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junbo","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Sun Yat\u2010Sen Memorial Hospital Sun Yat\u2010Sen University Guangzhou 510120 Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqing","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Sun Yat\u2010Sen Memorial Hospital Sun Yat\u2010Sen University Guangzhou 510120 Guangdong China"},{"name":"Department of Clinical Laboratory, Shenshan Central Hospital, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Shanwei 516600 Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongkang","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Sun Yat\u2010Sen Memorial Hospital Sun Yat\u2010Sen University Guangzhou 510120 Guangdong 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