{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T19:16:01Z","timestamp":1788030961420,"version":"build-2784847793"},"reference-count":59,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to assess cough symptom improvement following superior laryngeal nerve block (SLNB) in patients with neurogenic cough (NC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>Studies were systematically searched on PubMed, Embase, Web of Science, and Cochrane Library.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>Articles reporting SLNB for the treatment of NC were included. Outcomes of interest included subjective reporting of improvement, patient\u2010reported outcome measures, and adverse events. Mean difference (MD) was used for continuous outcomes and proportions for binary endpoints, with 95% confidence intervals (CI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eight retrospective studies involving 552 patients met inclusion criteria. The pooled proportion of subjective improvement of cough following SLNB was 74.04% (95% CI 68.61\u201078.81,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200913.6%). Patients experienced a statistically significant reduction in Cough Severity Index scores (MD \u22127.37, 95% CI \u221213.42 to \u22121.32,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.02,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200981.7%), with the greatest reduction in those who underwent 3 or more injections (MD \u221210.57, 95% CI \u221219.37 to \u22121.78,\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200933.4%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.02). Adverse events were minimal and self\u2010resolving, with 17.91% and 3.35% of patients experiencing local transient and systemic transient events, respectively. Injection\u2010limiting\/serious adverse events were rare, occurring in 1.97% of patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest that SLNB may benefit a substantial number of patients, as evidenced by improvements in both subjective reports and cough\u2010specific patient\u2010reported outcomes, while maintaining a favorable safety profile with minimal adverse events. Additionally, patients who received multiple injections generally experienced greater reductions in cough severity. Further large\u2010scale clinical trials are needed to confirm the efficacy and long\u2010term effects of this treatment modality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>II.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.70292","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T14:44:51Z","timestamp":1781880291000},"page":"501-514","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Superior Laryngeal Nerve Block for Neurogenic Cough: A Single\u2010Arm Meta\u2010Analysis"],"prefix":"10.1002","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7143-5085","authenticated-orcid":false,"given":"Thamiris D. 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V.","family":"Vendramini","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Jo\u00e3o del Rei, S\u00e3o Jo\u00e3o del Rei Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Plane","sequence":"additional","affiliation":[{"name":"University of Chile Medical School Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Evangelista P.","family":"Conrado","sequence":"additional","affiliation":[{"name":"Federal University of Cear\u00e1 Medical School Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Naunheim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Otolaryngology Massachusetts Eye and Ear Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25186"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-013-9508-y"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00027804"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00218714"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29146"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2024.104412"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.15.1657"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15-1496"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2013.1376"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26393"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25978"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.58.4.339"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.0972"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.59"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2015.01.001"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27201"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2015.02.013"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2018.11.002"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1213\/XAA.0000000000000136"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2018.71.2.120"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30739"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30570"},{"key":"e_1_2_9_24_1","first-page":"S08921997250000","article-title":"The efficacy of superior laryngeal nerve block for chronic cough: a scoping review","author":"McClutchy C","year":"2025","journal-title":"J Voice"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-025-00819-1"},{"key":"e_1_2_9_26_1","unstructured":"Cochrane Collaboration Handbook for Systematic Review of Interventions. 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