{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T17:04:07Z","timestamp":1785344647840,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the association between chronic rhinosinusitis (CRS) and Eustachian tube dysfunction (ETD) using subjective and objective measures, and the relationship between disease laterality and Eustachian tube function (ETF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single tertiary medical institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Eighty\u2010five CRS patients who were candidates for FESS underwent comprehensive evaluation. Subjective assessments utilized the Eustachian Tube Dysfunction Questionnaire\u20107 (ETDQ\u20107) and Sino\u2010Nasal Outcome Test\u201022 (SNOT\u201022). Objective evaluations comprised a 9\u2010step inflation\u2013deflation tympanometric test scored by maximal peak pressure difference (MPD), nasal endoscopy using the modified Lund\u2010Kennedy (MLK) system, sinus CT scored via the Lund\u2010Mackay (LM) system, and acoustic rhinometry measuring the second minimal cross\u2010sectional area (MCA\n                      <jats:sub>2<\/jats:sub>\n                      ). Patients were stratified into fair (&lt;14) and poor (\u226514) ETF groups based on ETDQ\u20107 scores. Correlations were analyzed using Pearson coefficients, receiver operating characteristic (ROC) curves, and Bland\u2010Altman plots, with additional assessment of CRS lateralization effects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Poor ETF (ETDQ\u20107\u2009\u2265\u200914) occurred in 36.5% of patients and was associated with higher SNOT\u201022 (median 48.0 vs 31.5,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.001). ETDQ\u20107 correlated moderately with SNOT\u201022 total (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.65). No significant differences in MPD, MLK, LM, or MCA\n                      <jats:sub>2<\/jats:sub>\n                      were found between fair and poor ET function groups. ROC analysis identified optimal cut\u2010offs of ETDQ\u20107\u2009&gt;\u200915 (AUC 0.761) and SNOT\u201022\u2009&gt;\u200945 (AUC 0.802). Laterality analysis showed no significant side\u2010specific associations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In CRS, sinonasal symptom burden shows only a moderate association with patient\u2010reported ETD. Higher ETDQ\u20107 scores often parallel greater SNOT\u201022 severity, suggesting that PROMs may help identify patients in whom ETD symptoms are partly influenced by CRS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ohn.70299","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T12:20:25Z","timestamp":1779452425000},"page":"326-334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Interplay Between Rhinosinusitis and Eustachian Tube Dysfunction in Patients Undergoing Functional Endoscopic Sinus Surgery"],"prefix":"10.1002","volume":"175","author":[{"given":"Jing\u2010Jie","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan"},{"name":"Department of Medicine, School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien\u2010Hsiang","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Brown University Warren Alpert Medical School Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Ting","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Taichung Veterans General Hospital Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong\u2010San","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Tungs' Taichung MetroHarbor Hospital Taichung Taiwan"},{"name":"Department of Medical Research Taichung Veterans General Hospital Taichung Taiwan"},{"name":"Department of Medicine, School of Medicine Chung Shan Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(83)90027-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12475"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14242810"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22942"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23341"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1989.01860330044014"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin21.209"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/npmj.npmj_31_23"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4193\/RHINOL\/18.050"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40521-023-00327-8"},{"key":"e_1_2_9_12_1","first-page":"77","article-title":"Sinonasal polyposis and its effect on eustachian tube function","volume":"9","author":"Mane SB","year":"2016","journal-title":"Clin Rhinol"},{"key":"e_1_2_9_13_1","first-page":"13","article-title":"Eustachian tube dysfunction diagnostic pathway\u2014what is the current state of the art and how relevant is chronic nasal disease?","volume":"13","author":"Anastasiadou S","year":"2024","journal-title":"J Clin Med"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin17.165"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23223"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2019.08.017"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2009.01995.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.121022"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948109000608"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947508400309"},{"key":"e_1_2_9_21_1","unstructured":"Grason\u2010Stadler. 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