{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:24:01Z","timestamp":1760955841704,"version":"build-2065373602"},"reference-count":50,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Otolaryngol.--head neck surg."],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the audiological characteristics of vestibular schwannoma (VS) patients with normal pure\u2010tone audiometry (PTA) results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>A retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Forty\u2010two VS patients with normal PTA results from October 2016 to October 2022 were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Normal PTA was defined when the hearing threshold is \u226425\u2009dB hearing loss (HL) in each test frequency and the PTA is \u226425\u2009dB HL. Results of multiple audiological tests such as the auditory brainstem response (ABR), distortion product otoacoustic emission (DPOAE), multiple auditory steady\u2010state responses threshold (ASSR), and speech discrimination score were retrospectively reviewed. Demographic data of these patients were also been collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>According to our results, the ABR and average ASSR threshold of the affected side were statistically significantly higher in VS patients with normal PTA. ABR waveforms on the affected side also showed more abnormalities. The DPOAE pass rates of the affected side were lower than the unaffected side while the amplitude and signal\u2010to\u2010noise ratio rate was also lower. In addition, we used magnetic resonance imaging 3\u2010dimensional reconstruction images to measure the volume of tumors in these patients. We also found that higher ABR threshold means lager tumor size in patients with normal PTA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>VS patients with normal PTA result cannot be assumed to have no impairment of hearing function. ABR, DPOAE, and ASSR results showed the characteristic changes in the affect ear. ABR threshold has the highest sensitivity for hearing abnormalities and is strong relative with tumor size in patients with normal PTA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ohn.783","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T09:19:38Z","timestamp":1714123178000},"page":"502-510","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Audiological Characteristics of Vestibular Schwannoma Patients With Normal Pure\u2010Tone Audiometry"],"prefix":"10.1002","volume":"171","author":[{"given":"Weixun","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Eye Ear Nose and Throat Hospital Fudan University Shanghai China"},{"name":"Research Institute of Otolaryngology Fudan University Shanghai China"},{"name":"Lateral Skull Base Diagnosis and Treatment Center, Eye Ear Nose and Throat Hospital Fudan University Shanghai 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