{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T14:51:31Z","timestamp":1675176691474},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:00:00Z","timestamp":1613692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Triage procedures have been implemented to limit hospital access and minimize infection risk among patients with cancer during the coronavirus disease (COVID-19) outbreak. In the absence of prospective evidence, we aimed to evaluate the predictive performance of a triage system in the oncological setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>This retrospective cohort study analyzes hospital admissions to the oncology and hematology department of Udine, Italy, during the COVID-19 pandemic (March 30 to April 30, 2020). A total of 3,923 triage procedures were performed, and data of 1,363 individual patients were reviewed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A self-report triage questionnaire identified 6% of triage-positive procedures, with a sensitivity of 66.7% (95% confidence interval [CI], 43.0%\u201385.4%), a specificity of 94.3% (95% CI, 93.5%\u201395.0%), and a positive predictive value of 5.9% (95% CI, 4.3%\u20138.0%) for the identification of patients who were not admitted to the hospital after medical review. Patients with thoracic cancer (odds ratio [OR], 1.69; 95% CI, 1.13\u20132.53, p = .01), younger age (OR, 1.52; 95% CI, 1.15\u20132.01, p &amp;lt; .01), and body temperature at admission \u226537\u00b0C (OR, 9.52; 95% CI, 5.44\u201316.6, p &amp;lt; .0001) had increased risk of positive triage. Direct hospital access was warranted to 93.5% of cases, a further 6% was accepted after medical evaluation, whereas 0.5% was refused at admission.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>A self-report questionnaire has a low positive predictive value to triage patients with cancer and suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) symptoms. Differential diagnosis with tumor- or treatment-related symptoms is always required to avoid unnecessary treatment delays. Body temperature measurement improves the triage process's overall sensitivity, and widespread SARS-CoV-2 testing should be implemented to identify asymptomatic carriers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Implications for Practice<\/jats:title>\n                  <jats:p>This is the first study to provide data on the predictive performance of a triage system in the oncological setting during the coronavirus disease outbreak. A questionnaire-based triage has a low positive predictive value to triage patients with cancer and suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) symptoms, and a differential diagnosis with tumor- or treatment-related symptoms is mandatory to avoid unnecessary treatment delays. Consequently, adequate recourses should be reallocated for a triage implementation in the oncological setting. Of note, body temperature measurement improves the overall sensitivity of the triage process, and widespread testing for SARS-CoV-2 infection should be implemented to identify asymptomatic carriers.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/onco.13706","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T07:02:14Z","timestamp":1612594934000},"page":"e694-e703","source":"Crossref","is-referenced-by-count":3,"title":["Feasibility and Predictive Performance of a Triage System for Patients with Cancer During the COVID-19 Pandemic"],"prefix":"10.1093","volume":"26","author":[{"given":"Gianpiero","family":"Fasola","sequence":"first","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Pelizzari","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Zara","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giada","family":"Targato","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Petruzzellis","sequence":"additional","affiliation":[{"name":"Department of Hematology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro Marco","family":"Minisini","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Bin","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaela","family":"Donato","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Mansutti","sequence":"additional","affiliation":[{"name":"Department of Oncology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Comuzzi","sequence":"additional","affiliation":[{"name":"Department of Hematology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Candoni","sequence":"additional","affiliation":[{"name":"Department of Hematology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Sperotto","sequence":"additional","affiliation":[{"name":"Department of Hematology, Santa Maria della Misericordia Hospital, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato","family":"Fanin","sequence":"additional","affiliation":[{"name":"Department of Hematology, Santa Maria della Misericordia Hospital, Udine, Italy"},{"name":"Department of Medicine, University of Udine, Udine, 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